KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF40B
All Species:
22.42
Human Site:
S124
Identified Species:
44.85
UniProt:
Q6NWY9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.36
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NWY9
NP_001026868.1
871
99358
S124
Q
S
V
W
E
K
P
S
V
L
K
S
K
A
E
Chimpanzee
Pan troglodytes
XP_001144883
893
101489
S146
Q
S
V
W
E
K
P
S
V
L
K
S
K
A
E
Rhesus Macaque
Macaca mulatta
XP_001101626
863
97737
S159
Q
S
V
W
E
K
P
S
V
L
K
S
K
A
E
Dog
Lupus familis
XP_534809
997
112581
S248
Q
S
V
W
E
K
P
S
V
L
K
S
K
A
E
Cat
Felis silvestris
Mouse
Mus musculus
Q80W14
870
99281
S124
Q
S
V
W
E
K
P
S
V
L
K
S
K
A
E
Rat
Rattus norvegicus
NP_001128055
867
99008
S124
Q
S
V
W
E
K
P
S
A
L
K
S
K
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508338
855
97709
D153
Q
S
T
W
E
K
P
D
D
L
K
T
P
A
E
Chicken
Gallus gallus
NP_989492
853
96992
D159
Q
S
T
W
E
K
P
D
D
L
K
T
P
A
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_938170
851
97677
D138
Q
S
T
W
E
K
P
D
E
L
K
S
P
A
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608738
806
91309
L91
L
M
T
P
A
E
L
L
H
N
Q
C
P
W
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34600
724
84646
H97
E
K
G
T
P
Y
Y
H
N
R
V
T
K
Q
T
Sea Urchin
Strong. purpuratus
XP_001178122
1501
164734
D208
Q
S
K
W
E
K
P
D
D
L
K
T
K
A
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
93.6
85
N.A.
95.5
95
N.A.
57
57.6
N.A.
60.8
N.A.
40.4
N.A.
31.9
34.6
Protein Similarity:
100
97.5
94
86
N.A.
97.5
97.1
N.A.
71.8
71.6
N.A.
74.7
N.A.
57.6
N.A.
52
44.3
P-Site Identity:
100
100
100
100
N.A.
100
93.3
N.A.
66.6
66.6
N.A.
73.3
N.A.
0
N.A.
6.6
73.3
P-Site Similarity:
100
100
100
100
N.A.
100
93.3
N.A.
73.3
73.3
N.A.
73.3
N.A.
20
N.A.
20
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
9
0
0
0
9
0
0
0
0
84
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
34
25
0
0
0
0
0
0
% D
% Glu:
9
0
0
0
84
9
0
0
9
0
0
0
0
0
84
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
9
9
0
0
84
0
0
0
0
84
0
67
0
9
% K
% Leu:
9
0
0
0
0
0
9
9
0
84
0
0
0
0
0
% L
% Met:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% N
% Pro:
0
0
0
9
9
0
84
0
0
0
0
0
34
0
0
% P
% Gln:
84
0
0
0
0
0
0
0
0
0
9
0
0
9
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% R
% Ser:
0
84
0
0
0
0
0
50
0
0
0
59
0
0
0
% S
% Thr:
0
0
34
9
0
0
0
0
0
0
0
34
0
0
9
% T
% Val:
0
0
50
0
0
0
0
0
42
0
9
0
0
0
0
% V
% Trp:
0
0
0
84
0
0
0
0
0
0
0
0
0
9
0
% W
% Tyr:
0
0
0
0
0
9
9
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _