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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF40B
All Species:
23.64
Human Site:
S670
Identified Species:
47.27
UniProt:
Q6NWY9
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NWY9
NP_001026868.1
871
99358
S670
F
E
Q
I
T
L
E
S
E
R
I
R
L
F
R
Chimpanzee
Pan troglodytes
XP_001144883
893
101489
S692
F
E
Q
I
T
L
E
S
E
R
I
R
L
F
R
Rhesus Macaque
Macaca mulatta
XP_001101626
863
97737
A675
F
R
S
M
L
R
Q
A
V
P
A
L
E
L
G
Dog
Lupus familis
XP_534809
997
112581
S796
F
E
Q
I
T
L
E
S
E
R
I
R
L
F
R
Cat
Felis silvestris
Mouse
Mus musculus
Q80W14
870
99281
S670
F
E
Q
I
T
L
E
S
E
R
I
R
L
F
R
Rat
Rattus norvegicus
NP_001128055
867
99008
S668
F
E
Q
I
T
L
E
S
E
R
I
R
L
F
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508338
855
97709
L661
L
D
A
G
N
I
K
L
A
F
N
S
L
L
E
Chicken
Gallus gallus
NP_989492
853
96992
L659
L
D
A
G
N
I
K
L
A
F
N
S
L
L
E
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_938170
851
97677
A651
F
K
S
M
L
K
Q
A
T
P
P
L
E
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608738
806
91309
E612
K
K
L
V
E
H
L
E
A
F
A
L
Y
E
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34600
724
84646
S535
T
T
E
Y
R
E
F
S
D
W
V
V
S
H
E
Sea Urchin
Strong. purpuratus
XP_001178122
1501
164734
S1066
F
D
G
I
T
V
E
S
E
R
I
R
L
F
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
93.6
85
N.A.
95.5
95
N.A.
57
57.6
N.A.
60.8
N.A.
40.4
N.A.
31.9
34.6
Protein Similarity:
100
97.5
94
86
N.A.
97.5
97.1
N.A.
71.8
71.6
N.A.
74.7
N.A.
57.6
N.A.
52
44.3
P-Site Identity:
100
100
6.6
100
N.A.
100
100
N.A.
6.6
6.6
N.A.
6.6
N.A.
0
N.A.
6.6
73.3
P-Site Similarity:
100
100
26.6
100
N.A.
100
100
N.A.
26.6
26.6
N.A.
33.3
N.A.
20
N.A.
26.6
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
17
0
0
0
0
17
25
0
17
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
25
0
0
0
0
0
0
9
0
0
0
0
0
0
% D
% Glu:
0
42
9
0
9
9
50
9
50
0
0
0
17
9
34
% E
% Phe:
67
0
0
0
0
0
9
0
0
25
0
0
0
50
0
% F
% Gly:
0
0
9
17
0
0
0
0
0
0
0
0
0
0
9
% G
% His:
0
0
0
0
0
9
0
0
0
0
0
0
0
9
0
% H
% Ile:
0
0
0
50
0
17
0
0
0
0
50
0
0
0
0
% I
% Lys:
9
17
0
0
0
9
17
0
0
0
0
0
0
0
17
% K
% Leu:
17
0
9
0
17
42
9
17
0
0
0
25
67
25
0
% L
% Met:
0
0
0
17
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
17
0
0
0
0
0
17
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
17
9
0
0
9
0
% P
% Gln:
0
0
42
0
0
0
17
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
0
0
9
9
0
0
0
50
0
50
0
0
42
% R
% Ser:
0
0
17
0
0
0
0
59
0
0
0
17
9
0
0
% S
% Thr:
9
9
0
0
50
0
0
0
9
0
0
0
0
0
0
% T
% Val:
0
0
0
9
0
9
0
0
9
0
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% W
% Tyr:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _