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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF40B
All Species:
24.85
Human Site:
S743
Identified Species:
49.7
UniProt:
Q6NWY9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NWY9
NP_001026868.1
871
99358
S743
R
N
P
S
E
S
G
S
E
P
S
S
S
L
D
Chimpanzee
Pan troglodytes
XP_001144883
893
101489
S765
R
N
P
S
E
S
G
S
E
P
S
S
S
L
D
Rhesus Macaque
Macaca mulatta
XP_001101626
863
97737
H745
K
H
H
R
K
R
S
H
S
P
S
G
S
E
S
Dog
Lupus familis
XP_534809
997
112581
S868
R
N
P
S
E
S
G
S
E
P
S
S
S
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80W14
870
99281
S743
R
N
P
S
E
S
G
S
E
P
S
S
S
L
D
Rat
Rattus norvegicus
NP_001128055
867
99008
S740
R
N
P
S
E
S
G
S
E
P
S
S
S
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508338
855
97709
K732
I
T
L
E
S
E
R
K
R
I
F
K
D
F
M
Chicken
Gallus gallus
NP_989492
853
96992
K730
I
T
L
E
S
E
R
K
R
I
F
K
D
F
M
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_938170
851
97677
S728
R
S
R
S
G
S
E
S
E
E
D
E
Y
H
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608738
806
91309
S685
R
R
R
S
K
T
R
S
H
S
L
T
S
I
G
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34600
724
84646
I607
W
T
V
I
K
P
K
I
E
K
D
K
A
Y
L
Sea Urchin
Strong. purpuratus
XP_001178122
1501
164734
S1182
T
P
V
S
D
S
G
S
D
E
K
E
S
G
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
93.6
85
N.A.
95.5
95
N.A.
57
57.6
N.A.
60.8
N.A.
40.4
N.A.
31.9
34.6
Protein Similarity:
100
97.5
94
86
N.A.
97.5
97.1
N.A.
71.8
71.6
N.A.
74.7
N.A.
57.6
N.A.
52
44.3
P-Site Identity:
100
100
20
100
N.A.
100
100
N.A.
0
0
N.A.
33.3
N.A.
26.6
N.A.
6.6
33.3
P-Site Similarity:
100
100
40
100
N.A.
100
100
N.A.
0
0
N.A.
40
N.A.
53.3
N.A.
20
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
9
0
0
0
9
0
17
0
17
0
42
% D
% Glu:
0
0
0
17
42
17
9
0
59
17
0
17
0
9
9
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
17
0
0
17
0
% F
% Gly:
0
0
0
0
9
0
50
0
0
0
0
9
0
9
9
% G
% His:
0
9
9
0
0
0
0
9
9
0
0
0
0
9
0
% H
% Ile:
17
0
0
9
0
0
0
9
0
17
0
0
0
9
0
% I
% Lys:
9
0
0
0
25
0
9
17
0
9
9
25
0
0
0
% K
% Leu:
0
0
17
0
0
0
0
0
0
0
9
0
0
42
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
17
% M
% Asn:
0
42
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
9
42
0
0
9
0
0
0
50
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
59
9
17
9
0
9
25
0
17
0
0
0
0
0
0
% R
% Ser:
0
9
0
67
17
59
9
67
9
9
50
42
67
0
9
% S
% Thr:
9
25
0
0
0
9
0
0
0
0
0
9
0
0
9
% T
% Val:
0
0
17
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
9
9
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _