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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRPF40B All Species: 25.15
Human Site: S798 Identified Species: 50.3
UniProt: Q6NWY9 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.27
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NWY9 NP_001026868.1 871 99358 S798 H K S N S P E S E T D P E E K
Chimpanzee Pan troglodytes XP_001144883 893 101489 S820 H K S N S P E S E T D P E E K
Rhesus Macaque Macaca mulatta XP_001101626 863 97737 R796 G G A A L G G R G S P S S H L
Dog Lupus familis XP_534809 997 112581 S924 H K S N S P E S E T D P E E K
Cat Felis silvestris
Mouse Mus musculus Q80W14 870 99281 S799 H K S T S P D S E T D P E D K
Rat Rattus norvegicus NP_001128055 867 99008 S796 H K S T S P D S E T D P E D K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508338 855 97709 K786 D D S H S K K K R Q R S E S R
Chicken Gallus gallus NP_989492 853 96992 K784 D D S H S K K K R Q R S E S R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_938170 851 97677 S781 H K S G S P E S E G E R E R K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608738 806 91309 N736 A L L Q N D S N S H S P A K K
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34600 724 84646 S659 K K K K N K R S D N N S E S E
Sea Urchin Strong. purpuratus XP_001178122 1501 164734 T1239 M R P T A H K T D S P C G R Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 93.6 85 N.A. 95.5 95 N.A. 57 57.6 N.A. 60.8 N.A. 40.4 N.A. 31.9 34.6
Protein Similarity: 100 97.5 94 86 N.A. 97.5 97.1 N.A. 71.8 71.6 N.A. 74.7 N.A. 57.6 N.A. 52 44.3
P-Site Identity: 100 100 0 100 N.A. 80 80 N.A. 20 20 N.A. 66.6 N.A. 13.3 N.A. 20 0
P-Site Similarity: 100 100 13.3 100 N.A. 93.3 93.3 N.A. 40 40 N.A. 73.3 N.A. 33.3 N.A. 46.6 46.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 9 9 0 0 0 0 0 0 0 9 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % C
% Asp: 17 17 0 0 0 9 17 0 17 0 42 0 0 17 0 % D
% Glu: 0 0 0 0 0 0 34 0 50 0 9 0 75 25 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 9 9 0 9 0 9 9 0 9 9 0 0 9 0 0 % G
% His: 50 0 0 17 0 9 0 0 0 9 0 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 59 9 9 0 25 25 17 0 0 0 0 0 9 59 % K
% Leu: 0 9 9 0 9 0 0 0 0 0 0 0 0 0 9 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 25 17 0 0 9 0 9 9 0 0 0 0 % N
% Pro: 0 0 9 0 0 50 0 0 0 0 17 50 0 0 0 % P
% Gln: 0 0 0 9 0 0 0 0 0 17 0 0 0 0 9 % Q
% Arg: 0 9 0 0 0 0 9 9 17 0 17 9 0 17 17 % R
% Ser: 0 0 67 0 67 0 9 59 9 17 9 34 9 25 0 % S
% Thr: 0 0 0 25 0 0 0 9 0 42 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _