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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRPF40B All Species: 22.12
Human Site: T786 Identified Species: 44.24
UniProt: Q6NWY9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NWY9 NP_001026868.1 871 99358 T786 A K K P K K K T K K R R H K S
Chimpanzee Pan troglodytes XP_001144883 893 101489 T808 A K K P K K K T K K R R H K S
Rhesus Macaque Macaca mulatta XP_001101626 863 97737 D784 S E P S S S L D S V E S G G A
Dog Lupus familis XP_534809 997 112581 T912 A K K P K K K T K K R R H K S
Cat Felis silvestris
Mouse Mus musculus Q80W14 870 99281 T787 T K K P K K K T K K R R H K S
Rat Rattus norvegicus NP_001128055 867 99008 T784 T K K P K K K T K K R R H K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508338 855 97709 S774 R S R S R S G S E S D D D D S
Chicken Gallus gallus NP_989492 853 96992 S772 R S R S R S G S E S E D D D S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_938170 851 97677 G769 S K K H K K K G K K R R H K S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_608738 806 91309 S724 S D V P G I Q S P G T Q A L L
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P34600 724 84646 K647 S E I L E K K K K K K D K K K
Sea Urchin Strong. purpuratus XP_001178122 1501 164734 G1227 K R P T L S P G D P Q P M R P
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 97.3 93.6 85 N.A. 95.5 95 N.A. 57 57.6 N.A. 60.8 N.A. 40.4 N.A. 31.9 34.6
Protein Similarity: 100 97.5 94 86 N.A. 97.5 97.1 N.A. 71.8 71.6 N.A. 74.7 N.A. 57.6 N.A. 52 44.3
P-Site Identity: 100 100 0 100 N.A. 93.3 93.3 N.A. 6.6 6.6 N.A. 80 N.A. 6.6 N.A. 33.3 0
P-Site Similarity: 100 100 20 100 N.A. 93.3 93.3 N.A. 33.3 33.3 N.A. 86.6 N.A. 33.3 N.A. 60 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 0 0 0 0 0 0 0 0 0 0 0 9 0 9 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 9 0 0 0 0 0 9 9 0 9 25 17 17 0 % D
% Glu: 0 17 0 0 9 0 0 0 17 0 17 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 9 0 17 17 0 9 0 0 9 9 0 % G
% His: 0 0 0 9 0 0 0 0 0 0 0 0 50 0 0 % H
% Ile: 0 0 9 0 0 9 0 0 0 0 0 0 0 0 0 % I
% Lys: 9 50 50 0 50 59 59 9 59 59 9 0 9 59 9 % K
% Leu: 0 0 0 9 9 0 9 0 0 0 0 0 0 9 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 17 50 0 0 9 0 9 9 0 9 0 0 9 % P
% Gln: 0 0 0 0 0 0 9 0 0 0 9 9 0 0 0 % Q
% Arg: 17 9 17 0 17 0 0 0 0 0 50 50 0 9 0 % R
% Ser: 34 17 0 25 9 34 0 25 9 17 0 9 0 0 67 % S
% Thr: 17 0 0 9 0 0 0 42 0 0 9 0 0 0 0 % T
% Val: 0 0 9 0 0 0 0 0 0 9 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _