KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF40B
All Species:
25.45
Human Site:
T842
Identified Species:
50.91
UniProt:
Q6NWY9
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NWY9
NP_001026868.1
871
99358
T842
F
G
I
K
K
E
K
T
G
W
D
T
S
E
S
Chimpanzee
Pan troglodytes
XP_001144883
893
101489
T864
F
G
I
K
K
E
K
T
G
W
D
T
S
E
S
Rhesus Macaque
Macaca mulatta
XP_001101626
863
97737
T834
F
G
I
K
K
E
K
T
G
W
D
T
S
E
S
Dog
Lupus familis
XP_534809
997
112581
T968
F
G
I
K
K
E
K
T
G
W
D
T
S
E
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80W14
870
99281
T841
F
G
I
K
K
E
K
T
G
W
D
T
S
E
S
Rat
Rattus norvegicus
NP_001128055
867
99008
T838
F
G
I
K
K
E
K
T
G
W
D
T
S
E
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508338
855
97709
G826
K
K
R
R
H
K
S
G
N
W
D
T
S
G
S
Chicken
Gallus gallus
NP_989492
853
96992
G824
K
K
R
R
H
K
S
G
N
W
D
T
S
G
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_938170
851
97677
G823
R
K
S
A
K
E
E
G
G
W
D
T
S
G
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608738
806
91309
S775
P
A
Q
S
V
E
S
S
G
S
R
N
E
E
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34600
724
84646
K697
E
R
G
K
K
S
K
K
S
R
K
R
S
P
S
Sea Urchin
Strong. purpuratus
XP_001178122
1501
164734
Y1437
S
S
I
T
S
A
W
Y
T
S
N
T
A
T
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
93.6
85
N.A.
95.5
95
N.A.
57
57.6
N.A.
60.8
N.A.
40.4
N.A.
31.9
34.6
Protein Similarity:
100
97.5
94
86
N.A.
97.5
97.1
N.A.
71.8
71.6
N.A.
74.7
N.A.
57.6
N.A.
52
44.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
33.3
33.3
N.A.
53.3
N.A.
20
N.A.
33.3
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
46.6
46.6
N.A.
60
N.A.
26.6
N.A.
33.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
9
0
9
0
0
0
0
0
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
75
0
0
0
0
% D
% Glu:
9
0
0
0
0
67
9
0
0
0
0
0
9
59
0
% E
% Phe:
50
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
50
9
0
0
0
0
25
67
0
0
0
0
25
0
% G
% His:
0
0
0
0
17
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
59
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
17
25
0
59
67
17
59
9
0
0
9
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
17
0
9
9
0
0
9
% N
% Pro:
9
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% P
% Gln:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
9
9
17
17
0
0
0
0
0
9
9
9
0
0
0
% R
% Ser:
9
9
9
9
9
9
25
9
9
17
0
0
84
0
84
% S
% Thr:
0
0
0
9
0
0
0
50
9
0
0
84
0
9
0
% T
% Val:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
9
0
0
75
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _