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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF40B
All Species:
37.88
Human Site:
Y109
Identified Species:
75.76
UniProt:
Q6NWY9
Number Species:
11
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NWY9
NP_001026868.1
871
99358
Y109
V
A
P
D
G
R
I
Y
Y
Y
N
A
D
D
K
Chimpanzee
Pan troglodytes
XP_001144883
893
101489
Y131
V
A
P
D
G
R
I
Y
Y
Y
N
A
D
D
K
Rhesus Macaque
Macaca mulatta
XP_001101626
863
97737
Y144
V
A
P
D
G
R
I
Y
Y
Y
N
A
D
D
K
Dog
Lupus familis
XP_534809
997
112581
Y233
V
A
P
D
G
R
I
Y
Y
Y
N
A
D
D
K
Cat
Felis silvestris
Mouse
Mus musculus
Q80W14
870
99281
Y109
V
A
P
D
G
R
I
Y
Y
Y
N
A
D
D
K
Rat
Rattus norvegicus
NP_001128055
867
99008
Y109
V
A
P
D
G
R
I
Y
Y
Y
N
A
D
D
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508338
855
97709
Y138
K
S
P
D
G
R
T
Y
Y
Y
N
T
E
T
K
Chicken
Gallus gallus
NP_989492
853
96992
Y144
K
S
P
D
G
R
T
Y
Y
Y
N
T
E
T
K
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_938170
851
97677
Y123
K
S
L
D
G
K
I
Y
Y
Y
N
T
E
T
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_608738
806
91309
S76
Y
N
Q
N
T
K
Q
S
S
W
E
K
P
E
A
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34600
724
84646
S82
H
S
S
P
S
V
E
S
D
W
S
V
H
T
N
Sea Urchin
Strong. purpuratus
XP_001178122
1501
164734
Y193
K
A
P
D
G
R
T
Y
F
Y
N
N
L
T
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.3
93.6
85
N.A.
95.5
95
N.A.
57
57.6
N.A.
60.8
N.A.
40.4
N.A.
31.9
34.6
Protein Similarity:
100
97.5
94
86
N.A.
97.5
97.1
N.A.
71.8
71.6
N.A.
74.7
N.A.
57.6
N.A.
52
44.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
60
60
N.A.
53.3
N.A.
0
N.A.
0
60
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
73.3
73.3
N.A.
73.3
N.A.
26.6
N.A.
20
66.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
59
0
0
0
0
0
0
0
0
0
50
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
84
0
0
0
0
9
0
0
0
50
50
0
% D
% Glu:
0
0
0
0
0
0
9
0
0
0
9
0
25
9
0
% E
% Phe:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
84
0
0
0
0
0
0
0
0
0
0
% G
% His:
9
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% H
% Ile:
0
0
0
0
0
0
59
0
0
0
0
0
0
0
0
% I
% Lys:
34
0
0
0
0
17
0
0
0
0
0
9
0
0
84
% K
% Leu:
0
0
9
0
0
0
0
0
0
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
9
0
9
0
0
0
0
0
0
84
9
0
0
9
% N
% Pro:
0
0
75
9
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
9
0
0
0
9
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
75
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
34
9
0
9
0
0
17
9
0
9
0
0
0
0
% S
% Thr:
0
0
0
0
9
0
25
0
0
0
0
25
0
42
0
% T
% Val:
50
0
0
0
0
9
0
0
0
0
0
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% W
% Tyr:
9
0
0
0
0
0
0
84
75
84
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _