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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ESRP1 All Species: 30.91
Human Site: S135 Identified Species: 52.31
UniProt: Q6NXG1 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NXG1 NP_001030087.2 681 75585 S135 L L P E C F Y S F F D L R K E
Chimpanzee Pan troglodytes XP_519861 568 63333 R54 Q L H E V L V R P D Q L E L T
Rhesus Macaque Macaca mulatta XP_001098015 715 77120 S155 V L P D T F F S F Y D L R R E
Dog Lupus familis XP_544182 682 75615 S140 L L P E C F Y S F F D L R K E
Cat Felis silvestris
Mouse Mus musculus Q3US41 680 75531 S135 L L P E C F Y S F F D L R K E
Rat Rattus norvegicus B2RYD2 677 75002 S135 L L P E C F Y S F F D L R K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507064 513 56739
Chicken Gallus gallus Q5ZLR4 701 76929 S136 L L S D C F Y S F Y D L R K E
Frog Xenopus laevis Q7ZY29 688 76408 S136 L L P E C F Y S F F D L R K E
Zebra Danio Brachydanio rerio Q7ZVR8 736 80812 T135 V L P E C F Y T F V D L K K E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9BJZ5 967 102725 D189 F L R Y K S G D L A R A L V P
Honey Bee Apis mellifera XP_397080 746 80915 K119 T L F H D L R K E F V A C Y S
Nematode Worm Caenorhab. elegans Q22708 618 69158 L104 P L F A R N E L C V P H P L H
Sea Urchin Strong. purpuratus XP_792820 752 83177 N133 P I P E Y F Y N F F D L R K E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 82.2 58.8 90.9 N.A. 97 95.7 N.A. 71.8 67.9 84.4 62.7 N.A. 35.3 40 31.8 43.7
Protein Similarity: 100 83.1 72.5 92.6 N.A. 98.2 97.2 N.A. 73.8 78.5 92.4 74.5 N.A. 47.5 53.8 49.7 60.5
P-Site Identity: 100 20 60 100 N.A. 100 100 N.A. 0 80 100 73.3 N.A. 6.6 13.3 6.6 73.3
P-Site Similarity: 100 20 93.3 100 N.A. 100 100 N.A. 0 93.3 100 93.3 N.A. 6.6 13.3 6.6 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 8 0 0 0 0 0 8 0 15 0 0 0 % A
% Cys: 0 0 0 0 50 0 0 0 8 0 0 0 8 0 0 % C
% Asp: 0 0 0 15 8 0 0 8 0 8 65 0 0 0 0 % D
% Glu: 0 0 0 58 0 0 8 0 8 0 0 0 8 0 65 % E
% Phe: 8 0 15 0 0 65 8 0 65 50 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 8 8 0 0 0 0 0 0 0 8 0 0 8 % H
% Ile: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 8 0 0 8 0 0 0 0 8 58 0 % K
% Leu: 43 86 0 0 0 15 0 8 8 0 0 72 8 15 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 8 0 8 0 0 0 0 0 0 0 % N
% Pro: 15 0 58 0 0 0 0 0 8 0 8 0 8 0 8 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % Q
% Arg: 0 0 8 0 8 0 8 8 0 0 8 0 58 8 0 % R
% Ser: 0 0 8 0 0 8 0 50 0 0 0 0 0 0 8 % S
% Thr: 8 0 0 0 8 0 0 8 0 0 0 0 0 0 8 % T
% Val: 15 0 0 0 8 0 8 0 0 15 8 0 0 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 8 8 0 58 0 0 15 0 0 0 8 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _