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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESRP1
All Species:
18.18
Human Site:
S179
Identified Species:
30.77
UniProt:
Q6NXG1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NXG1
NP_001030087.2
681
75585
S179
S
V
S
R
Y
G
A
S
Q
V
E
D
M
G
N
Chimpanzee
Pan troglodytes
XP_519861
568
63333
I98
S
V
S
N
E
L
N
I
G
V
G
T
S
F
C
Rhesus Macaque
Macaca mulatta
XP_001098015
715
77120
W199
T
E
D
D
F
G
V
W
E
V
K
T
M
V
A
Dog
Lupus familis
XP_544182
682
75615
S184
L
V
S
R
Y
G
A
S
Q
V
E
D
M
G
N
Cat
Felis silvestris
Mouse
Mus musculus
Q3US41
680
75531
S179
S
V
S
R
Y
G
A
S
Q
V
E
D
M
G
N
Rat
Rattus norvegicus
B2RYD2
677
75002
S179
S
M
S
R
Y
G
A
S
Q
V
E
D
M
G
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507064
513
56739
N43
F
S
D
P
E
R
V
N
Y
K
F
E
S
G
T
Chicken
Gallus gallus
Q5ZLR4
701
76929
W180
A
E
E
D
F
G
V
W
Q
V
K
T
M
V
A
Frog
Xenopus laevis
Q7ZY29
688
76408
S180
T
H
Y
R
Y
G
A
S
E
V
D
D
M
G
D
Zebra Danio
Brachydanio rerio
Q7ZVR8
736
80812
E179
E
Q
E
A
G
L
R
E
V
K
D
M
V
L
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9BJZ5
967
102725
Y233
S
V
E
D
N
D
F
Y
I
R
E
S
R
D
M
Honey Bee
Apis mellifera
XP_397080
746
80915
C163
K
E
I
Q
D
M
I
C
V
I
Q
R
M
I
K
Nematode Worm
Caenorhab. elegans
Q22708
618
69158
D148
A
R
A
I
L
D
M
D
D
E
L
L
E
K
T
Sea Urchin
Strong. purpuratus
XP_792820
752
83177
E177
Y
T
E
T
G
L
D
E
C
R
T
M
A
S
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.2
58.8
90.9
N.A.
97
95.7
N.A.
71.8
67.9
84.4
62.7
N.A.
35.3
40
31.8
43.7
Protein Similarity:
100
83.1
72.5
92.6
N.A.
98.2
97.2
N.A.
73.8
78.5
92.4
74.5
N.A.
47.5
53.8
49.7
60.5
P-Site Identity:
100
26.6
20
93.3
N.A.
100
93.3
N.A.
6.6
26.6
60
0
N.A.
20
6.6
0
0
P-Site Similarity:
100
26.6
46.6
93.3
N.A.
100
100
N.A.
20
46.6
86.6
13.3
N.A.
20
26.6
13.3
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
8
8
0
0
36
0
0
0
0
0
8
0
15
% A
% Cys:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
8
% C
% Asp:
0
0
15
22
8
15
8
8
8
0
15
36
0
8
8
% D
% Glu:
8
22
29
0
15
0
0
15
15
8
36
8
8
0
0
% E
% Phe:
8
0
0
0
15
0
8
0
0
0
8
0
0
8
0
% F
% Gly:
0
0
0
0
15
50
0
0
8
0
8
0
0
43
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
8
0
0
8
8
8
8
0
0
0
8
8
% I
% Lys:
8
0
0
0
0
0
0
0
0
15
15
0
0
8
8
% K
% Leu:
8
0
0
0
8
22
0
0
0
0
8
8
0
8
8
% L
% Met:
0
8
0
0
0
8
8
0
0
0
0
15
58
0
8
% M
% Asn:
0
0
0
8
8
0
8
8
0
0
0
0
0
0
29
% N
% Pro:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
8
0
0
0
0
36
0
8
0
0
0
0
% Q
% Arg:
0
8
0
36
0
8
8
0
0
15
0
8
8
0
0
% R
% Ser:
36
8
36
0
0
0
0
36
0
0
0
8
15
8
0
% S
% Thr:
15
8
0
8
0
0
0
0
0
0
8
22
0
0
15
% T
% Val:
0
36
0
0
0
0
22
0
15
58
0
0
8
15
0
% V
% Trp:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% W
% Tyr:
8
0
8
0
36
0
0
8
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _