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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESRP1
All Species:
23.33
Human Site:
S216
Identified Species:
39.49
UniProt:
Q6NXG1
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NXG1
NP_001030087.2
681
75585
S216
K
F
E
S
G
T
C
S
K
M
E
L
I
D
D
Chimpanzee
Pan troglodytes
XP_519861
568
63333
S135
L
L
P
E
C
F
Y
S
F
F
D
L
R
K
E
Rhesus Macaque
Macaca mulatta
XP_001098015
715
77120
S236
K
Y
E
T
G
P
C
S
K
A
D
V
V
D
S
Dog
Lupus familis
XP_544182
682
75615
S221
K
F
E
S
G
T
C
S
K
M
E
L
I
D
D
Cat
Felis silvestris
Mouse
Mus musculus
Q3US41
680
75531
K216
K
F
E
S
G
T
C
K
M
E
L
I
D
D
S
Rat
Rattus norvegicus
B2RYD2
677
75002
S216
K
F
E
S
G
T
C
S
K
T
E
L
I
D
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507064
513
56739
F80
S
D
Q
D
I
A
R
F
F
K
G
L
N
I
A
Chicken
Gallus gallus
Q5ZLR4
701
76929
S217
K
Y
E
T
G
P
C
S
K
S
E
T
V
D
S
Frog
Xenopus laevis
Q7ZY29
688
76408
S217
K
F
E
S
G
T
C
S
K
L
E
M
I
D
D
Zebra Danio
Brachydanio rerio
Q7ZVR8
736
80812
K216
F
E
S
G
A
C
S
K
T
E
A
V
D
S
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9BJZ5
967
102725
S270
V
L
E
P
G
I
C
S
I
D
D
E
V
D
G
Honey Bee
Apis mellifera
XP_397080
746
80915
C200
D
E
E
V
D
N
G
C
V
V
R
A
R
G
L
Nematode Worm
Caenorhab. elegans
Q22708
618
69158
A185
G
D
N
V
V
C
R
A
R
G
L
P
W
Q
A
Sea Urchin
Strong. purpuratus
XP_792820
752
83177
D214
P
G
T
Y
D
K
T
D
S
I
P
D
D
T
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.2
58.8
90.9
N.A.
97
95.7
N.A.
71.8
67.9
84.4
62.7
N.A.
35.3
40
31.8
43.7
Protein Similarity:
100
83.1
72.5
92.6
N.A.
98.2
97.2
N.A.
73.8
78.5
92.4
74.5
N.A.
47.5
53.8
49.7
60.5
P-Site Identity:
100
13.3
46.6
100
N.A.
53.3
86.6
N.A.
6.6
53.3
86.6
0
N.A.
33.3
6.6
0
0
P-Site Similarity:
100
26.6
80
100
N.A.
60
86.6
N.A.
13.3
73.3
100
13.3
N.A.
46.6
13.3
13.3
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
8
0
8
8
8
0
0
22
% A
% Cys:
0
0
0
0
8
15
58
8
0
0
0
0
0
0
0
% C
% Asp:
8
15
0
8
15
0
0
8
0
8
22
8
22
58
22
% D
% Glu:
0
15
65
8
0
0
0
0
0
15
36
8
0
0
15
% E
% Phe:
8
36
0
0
0
8
0
8
15
8
0
0
0
0
0
% F
% Gly:
8
8
0
8
58
0
8
0
0
8
8
0
0
8
15
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
8
0
0
8
8
0
8
29
8
0
% I
% Lys:
50
0
0
0
0
8
0
15
43
8
0
0
0
8
0
% K
% Leu:
8
15
0
0
0
0
0
0
0
8
15
36
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
8
15
0
8
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
0
0
0
0
8
0
0
% N
% Pro:
8
0
8
8
0
15
0
0
0
0
8
8
0
0
0
% P
% Gln:
0
0
8
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
15
0
8
0
8
0
15
0
0
% R
% Ser:
8
0
8
36
0
0
8
58
8
8
0
0
0
8
22
% S
% Thr:
0
0
8
15
0
36
8
0
8
8
0
8
0
8
0
% T
% Val:
8
0
0
15
8
0
0
0
8
8
0
15
22
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% W
% Tyr:
0
15
0
8
0
0
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _