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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESRP1
All Species:
26.97
Human Site:
S25
Identified Species:
45.64
UniProt:
Q6NXG1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NXG1
NP_001030087.2
681
75585
S25
A
T
G
A
K
L
G
S
D
E
K
E
L
I
L
Chimpanzee
Pan troglodytes
XP_519861
568
63333
Rhesus Macaque
Macaca mulatta
XP_001098015
715
77120
S45
A
L
G
R
D
L
G
S
D
E
T
D
L
I
L
Dog
Lupus familis
XP_544182
682
75615
D33
Q
S
K
E
S
K
H
D
G
Q
E
K
A
R
K
Cat
Felis silvestris
Mouse
Mus musculus
Q3US41
680
75531
S25
A
T
G
A
K
L
G
S
D
E
K
E
L
I
L
Rat
Rattus norvegicus
B2RYD2
677
75002
S25
A
T
G
A
K
L
G
S
D
E
K
E
L
I
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507064
513
56739
Chicken
Gallus gallus
Q5ZLR4
701
76929
S26
A
Y
G
A
K
L
G
S
D
E
R
E
L
I
L
Frog
Xenopus laevis
Q7ZY29
688
76408
S26
A
N
G
S
K
L
G
S
D
E
K
E
V
I
Q
Zebra Danio
Brachydanio rerio
Q7ZVR8
736
80812
S25
A
N
G
G
K
L
G
S
D
E
R
E
L
I
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9BJZ5
967
102725
T47
S
T
G
Q
I
V
G
T
K
Q
I
L
V
R
P
Honey Bee
Apis mellifera
XP_397080
746
80915
A28
G
T
G
S
D
N
P
A
V
A
G
S
S
G
V
Nematode Worm
Caenorhab. elegans
Q22708
618
69158
I15
P
E
Q
R
L
L
L
I
R
V
S
D
G
N
Y
Sea Urchin
Strong. purpuratus
XP_792820
752
83177
E25
G
A
L
L
G
T
D
E
E
D
L
V
L
L
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.2
58.8
90.9
N.A.
97
95.7
N.A.
71.8
67.9
84.4
62.7
N.A.
35.3
40
31.8
43.7
Protein Similarity:
100
83.1
72.5
92.6
N.A.
98.2
97.2
N.A.
73.8
78.5
92.4
74.5
N.A.
47.5
53.8
49.7
60.5
P-Site Identity:
100
0
66.6
0
N.A.
100
100
N.A.
0
86.6
73.3
80
N.A.
20
13.3
6.6
6.6
P-Site Similarity:
100
0
73.3
26.6
N.A.
100
100
N.A.
0
93.3
86.6
86.6
N.A.
53.3
33.3
13.3
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
50
8
0
29
0
0
0
8
0
8
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
15
0
8
8
50
8
0
15
0
0
0
% D
% Glu:
0
8
0
8
0
0
0
8
8
50
8
43
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
0
65
8
8
0
58
0
8
0
8
0
8
8
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
8
0
0
8
0
0
8
0
0
50
0
% I
% Lys:
0
0
8
0
43
8
0
0
8
0
29
8
0
0
8
% K
% Leu:
0
8
8
8
8
58
8
0
0
0
8
8
50
8
43
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
15
0
0
0
8
0
0
0
0
0
0
0
8
0
% N
% Pro:
8
0
0
0
0
0
8
0
0
0
0
0
0
0
8
% P
% Gln:
8
0
8
8
0
0
0
0
0
15
0
0
0
0
8
% Q
% Arg:
0
0
0
15
0
0
0
0
8
0
15
0
0
15
0
% R
% Ser:
8
8
0
15
8
0
0
50
0
0
8
8
8
0
0
% S
% Thr:
0
36
0
0
0
8
0
8
0
0
8
0
0
0
0
% T
% Val:
0
0
0
0
0
8
0
0
8
8
0
8
15
0
15
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _