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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESRP1
All Species:
13.94
Human Site:
S576
Identified Species:
23.59
UniProt:
Q6NXG1
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NXG1
NP_001030087.2
681
75585
S576
E
A
A
I
Y
Q
P
S
V
I
L
N
P
R
A
Chimpanzee
Pan troglodytes
XP_519861
568
63333
F464
T
I
E
D
I
L
D
F
L
G
E
F
A
T
D
Rhesus Macaque
Macaca mulatta
XP_001098015
715
77120
P594
T
E
T
A
A
L
Y
P
S
S
A
L
L
P
A
Dog
Lupus familis
XP_544182
682
75615
S577
E
A
A
I
Y
Q
P
S
V
L
L
N
P
R
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3US41
680
75531
S575
E
A
A
I
Y
Q
P
S
L
L
L
N
P
R
A
Rat
Rattus norvegicus
B2RYD2
677
75002
S572
E
A
A
I
Y
Q
P
S
L
L
L
N
P
R
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507064
513
56739
V409
A
A
L
Y
Q
P
S
V
L
L
N
P
R
T
L
Chicken
Gallus gallus
Q5ZLR4
701
76929
P578
Y
Q
P
Q
A
L
L
P
T
A
R
T
P
Q
A
Frog
Xenopus laevis
Q7ZY29
688
76408
P577
E
A
A
A
L
Y
Q
P
S
L
L
L
N
P
R
Zebra Danio
Brachydanio rerio
Q7ZVR8
736
80812
P581
T
E
A
A
L
Y
Q
P
P
L
L
A
T
P
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9BJZ5
967
102725
A681
G
Q
S
P
T
T
V
A
A
G
T
A
Q
S
P
Honey Bee
Apis mellifera
XP_397080
746
80915
P552
V
P
V
P
T
A
Q
P
P
L
W
D
I
H
A
Nematode Worm
Caenorhab. elegans
Q22708
618
69158
Y514
P
Q
Q
F
W
S
S
Y
P
S
P
P
I
S
P
Sea Urchin
Strong. purpuratus
XP_792820
752
83177
H627
A
A
A
G
L
G
H
H
Q
L
P
P
G
A
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.2
58.8
90.9
N.A.
97
95.7
N.A.
71.8
67.9
84.4
62.7
N.A.
35.3
40
31.8
43.7
Protein Similarity:
100
83.1
72.5
92.6
N.A.
98.2
97.2
N.A.
73.8
78.5
92.4
74.5
N.A.
47.5
53.8
49.7
60.5
P-Site Identity:
100
0
6.6
93.3
N.A.
86.6
86.6
N.A.
6.6
13.3
26.6
13.3
N.A.
0
6.6
0
13.3
P-Site Similarity:
100
6.6
6.6
100
N.A.
100
100
N.A.
20
20
33.3
20
N.A.
13.3
20
6.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
50
50
22
15
8
0
8
8
8
8
15
8
8
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
8
0
0
8
0
0
0
0
8
0
0
8
% D
% Glu:
36
15
8
0
0
0
0
0
0
0
8
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
0
8
0
0
0
8
0
0
0
% F
% Gly:
8
0
0
8
0
8
0
0
0
15
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
8
8
0
0
0
0
0
8
0
% H
% Ile:
0
8
0
29
8
0
0
0
0
8
0
0
15
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
8
0
22
22
8
0
29
58
43
15
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
29
8
0
0
% N
% Pro:
8
8
8
15
0
8
29
36
22
0
15
22
36
22
15
% P
% Gln:
0
22
8
8
8
29
22
0
8
0
0
0
8
8
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
8
0
8
29
15
% R
% Ser:
0
0
8
0
0
8
15
29
15
15
0
0
0
15
0
% S
% Thr:
22
0
8
0
15
8
0
0
8
0
8
8
8
15
8
% T
% Val:
8
0
8
0
0
0
8
8
15
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
8
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
8
0
0
8
29
15
8
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _