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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESRP1
All Species:
13.64
Human Site:
S614
Identified Species:
23.08
UniProt:
Q6NXG1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NXG1
NP_001030087.2
681
75585
S614
S
P
P
G
S
P
N
S
L
G
Y
F
P
T
A
Chimpanzee
Pan troglodytes
XP_519861
568
63333
F502
M
K
S
A
D
R
A
F
M
A
A
Q
K
C
H
Rhesus Macaque
Macaca mulatta
XP_001098015
715
77120
P632
Y
T
A
Y
Y
P
S
P
P
V
S
P
T
T
V
Dog
Lupus familis
XP_544182
682
75615
S615
S
S
P
G
S
P
T
S
L
G
Y
F
P
T
A
Cat
Felis silvestris
Mouse
Mus musculus
Q3US41
680
75531
S613
S
P
P
G
S
P
N
S
L
G
Y
F
P
T
A
Rat
Rattus norvegicus
B2RYD2
677
75002
S610
S
P
P
G
S
P
N
S
L
G
Y
F
P
T
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507064
513
56739
L447
P
P
G
S
P
S
N
L
G
Y
F
P
T
A
A
Chicken
Gallus gallus
Q5ZLR4
701
76929
V616
A
Y
Y
P
S
P
P
V
S
P
T
T
V
G
Y
Frog
Xenopus laevis
Q7ZY29
688
76408
P615
Y
P
S
P
P
G
S
P
S
S
L
G
F
F
P
Zebra Danio
Brachydanio rerio
Q7ZVR8
736
80812
Y619
M
N
M
S
Y
T
T
Y
Y
P
S
P
P
V
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9BJZ5
967
102725
H719
A
A
A
A
A
A
H
H
G
L
S
A
S
S
A
Honey Bee
Apis mellifera
XP_397080
746
80915
W590
A
I
R
N
Q
D
F
W
L
M
A
L
A
S
N
Nematode Worm
Caenorhab. elegans
Q22708
618
69158
E552
V
A
N
F
T
T
P
E
H
T
V
D
N
V
L
Sea Urchin
Strong. purpuratus
XP_792820
752
83177
G665
G
H
Q
L
Y
Y
P
G
A
A
T
G
N
N
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.2
58.8
90.9
N.A.
97
95.7
N.A.
71.8
67.9
84.4
62.7
N.A.
35.3
40
31.8
43.7
Protein Similarity:
100
83.1
72.5
92.6
N.A.
98.2
97.2
N.A.
73.8
78.5
92.4
74.5
N.A.
47.5
53.8
49.7
60.5
P-Site Identity:
100
0
13.3
86.6
N.A.
100
100
N.A.
20
13.3
6.6
6.6
N.A.
6.6
6.6
0
6.6
P-Site Similarity:
100
6.6
20
86.6
N.A.
100
100
N.A.
26.6
20
13.3
13.3
N.A.
33.3
20
6.6
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
22
15
15
15
8
8
8
0
8
15
15
8
8
8
50
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
8
8
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
8
0
0
8
8
0
0
8
29
8
8
0
% F
% Gly:
8
0
8
29
0
8
0
8
15
29
0
15
0
8
0
% G
% His:
0
8
0
0
0
0
8
8
8
0
0
0
0
0
8
% H
% Ile:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
0
0
8
0
0
% K
% Leu:
0
0
0
8
0
0
0
8
36
8
8
8
0
0
8
% L
% Met:
15
0
8
0
0
0
0
0
8
8
0
0
0
0
0
% M
% Asn:
0
8
8
8
0
0
29
0
0
0
0
0
15
8
8
% N
% Pro:
8
36
29
15
15
43
22
15
8
15
0
22
36
0
8
% P
% Gln:
0
0
8
0
8
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% R
% Ser:
29
8
15
15
36
8
15
29
15
8
22
0
8
15
8
% S
% Thr:
0
8
0
0
8
15
15
0
0
8
15
8
15
36
0
% T
% Val:
8
0
0
0
0
0
0
8
0
8
8
0
8
15
8
% V
% Trp:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% W
% Tyr:
15
8
8
8
22
8
0
8
8
8
29
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _