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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESRP1
All Species:
6.36
Human Site:
S74
Identified Species:
10.77
UniProt:
Q6NXG1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.23
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NXG1
NP_001030087.2
681
75585
S74
E
T
K
I
D
V
E
S
L
S
S
A
S
Q
L
Chimpanzee
Pan troglodytes
XP_519861
568
63333
Rhesus Macaque
Macaca mulatta
XP_001098015
715
77120
S94
A
S
G
L
S
A
D
S
L
A
R
A
E
P
L
Dog
Lupus familis
XP_544182
682
75615
S79
E
T
K
I
D
A
D
S
L
S
S
A
P
Q
L
Cat
Felis silvestris
Mouse
Mus musculus
Q3US41
680
75531
N74
E
T
K
I
D
A
E
N
L
S
S
A
P
Q
L
Rat
Rattus norvegicus
B2RYD2
677
75002
N74
E
T
K
I
D
A
E
N
L
S
S
A
P
Q
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507064
513
56739
Chicken
Gallus gallus
Q5ZLR4
701
76929
G75
V
S
G
L
T
A
E
G
L
G
K
A
E
P
L
Frog
Xenopus laevis
Q7ZY29
688
76408
D75
I
T
Q
I
E
T
D
D
L
Y
V
A
P
Q
L
Zebra Danio
Brachydanio rerio
Q7ZVR8
736
80812
E74
E
T
G
L
T
A
E
E
L
C
K
A
E
P
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9BJZ5
967
102725
E128
P
L
S
E
A
I
E
E
F
D
A
Y
L
R
S
Honey Bee
Apis mellifera
XP_397080
746
80915
P58
T
V
R
E
H
G
I
P
L
E
Q
A
I
Q
Q
Nematode Worm
Caenorhab. elegans
Q22708
618
69158
N43
R
R
Q
E
D
A
N
N
N
S
T
S
P
S
S
Sea Urchin
Strong. purpuratus
XP_792820
752
83177
V72
T
L
S
I
R
P
D
V
I
T
G
A
A
N
L
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.2
58.8
90.9
N.A.
97
95.7
N.A.
71.8
67.9
84.4
62.7
N.A.
35.3
40
31.8
43.7
Protein Similarity:
100
83.1
72.5
92.6
N.A.
98.2
97.2
N.A.
73.8
78.5
92.4
74.5
N.A.
47.5
53.8
49.7
60.5
P-Site Identity:
100
0
26.6
80
N.A.
80
80
N.A.
0
26.6
40
40
N.A.
6.6
20
13.3
20
P-Site Similarity:
100
0
53.3
86.6
N.A.
86.6
86.6
N.A.
0
40
60
46.6
N.A.
26.6
26.6
40
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
8
50
0
0
0
8
8
72
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
0
0
0
36
0
29
8
0
8
0
0
0
0
0
% D
% Glu:
36
0
0
22
8
0
43
15
0
8
0
0
22
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% F
% Gly:
0
0
22
0
0
8
0
8
0
8
8
0
0
0
0
% G
% His:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
0
43
0
8
8
0
8
0
0
0
8
0
0
% I
% Lys:
0
0
29
0
0
0
0
0
0
0
15
0
0
0
0
% K
% Leu:
0
15
0
22
0
0
0
0
65
0
0
0
8
0
65
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
8
22
8
0
0
0
0
8
0
% N
% Pro:
8
0
0
0
0
8
0
8
0
0
0
0
36
22
0
% P
% Gln:
0
0
15
0
0
0
0
0
0
0
8
0
0
43
8
% Q
% Arg:
8
8
8
0
8
0
0
0
0
0
8
0
0
8
0
% R
% Ser:
0
15
15
0
8
0
0
22
0
36
29
8
8
8
15
% S
% Thr:
15
43
0
0
15
8
0
0
0
8
8
0
0
0
0
% T
% Val:
8
8
0
0
0
8
0
8
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _