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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESRP1
All Species:
14.55
Human Site:
Y605
Identified Species:
24.62
UniProt:
Q6NXG1
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NXG1
NP_001030087.2
681
75585
Y605
F
M
N
Y
T
A
Y
Y
P
S
P
P
G
S
P
Chimpanzee
Pan troglodytes
XP_519861
568
63333
I493
R
P
S
G
D
A
F
I
Q
M
K
S
A
D
R
Rhesus Macaque
Macaca mulatta
XP_001098015
715
77120
L623
G
P
A
T
Q
L
Y
L
N
Y
T
A
Y
Y
P
Dog
Lupus familis
XP_544182
682
75615
Y606
F
M
N
Y
T
A
Y
Y
P
S
S
P
G
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q3US41
680
75531
Y604
F
M
N
Y
T
A
Y
Y
P
S
P
P
G
S
P
Rat
Rattus norvegicus
B2RYD2
677
75002
Y601
F
M
N
Y
T
A
Y
Y
P
S
P
P
G
S
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507064
513
56739
P438
M
N
Y
T
A
Y
Y
P
S
P
P
G
S
P
S
Chicken
Gallus gallus
Q5ZLR4
701
76929
Y607
A
A
Q
L
Y
M
N
Y
T
A
Y
Y
P
S
P
Frog
Xenopus laevis
Q7ZY29
688
76408
A606
Q
L
F
M
N
Y
T
A
Y
Y
P
S
P
P
G
Zebra Danio
Brachydanio rerio
Q7ZVR8
736
80812
M610
Y
Y
S
P
Q
L
Y
M
N
M
N
M
S
Y
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9BJZ5
967
102725
A710
H
A
H
A
T
G
H
A
H
A
A
A
A
A
A
Honey Bee
Apis mellifera
XP_397080
746
80915
A581
Q
A
Q
A
Q
A
Q
A
Q
A
I
R
N
Q
D
Nematode Worm
Caenorhab. elegans
Q22708
618
69158
E543
H
M
S
I
G
V
P
E
L
V
A
N
F
T
T
Sea Urchin
Strong. purpuratus
XP_792820
752
83177
P656
F
P
S
P
P
V
S
P
T
G
H
Q
L
Y
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
82.2
58.8
90.9
N.A.
97
95.7
N.A.
71.8
67.9
84.4
62.7
N.A.
35.3
40
31.8
43.7
Protein Similarity:
100
83.1
72.5
92.6
N.A.
98.2
97.2
N.A.
73.8
78.5
92.4
74.5
N.A.
47.5
53.8
49.7
60.5
P-Site Identity:
100
6.6
13.3
93.3
N.A.
100
100
N.A.
13.3
20
6.6
6.6
N.A.
6.6
6.6
6.6
6.6
P-Site Similarity:
100
20
13.3
93.3
N.A.
100
100
N.A.
13.3
26.6
13.3
20
N.A.
33.3
13.3
20
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
22
8
15
8
43
0
22
0
22
15
15
15
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
8
8
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% E
% Phe:
36
0
8
0
0
0
8
0
0
0
0
0
8
0
0
% F
% Gly:
8
0
0
8
8
8
0
0
0
8
0
8
29
0
8
% G
% His:
15
0
8
0
0
0
8
0
8
0
8
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
8
0
0
8
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
8
0
8
0
15
0
8
8
0
0
0
8
0
0
% L
% Met:
8
36
0
8
0
8
0
8
0
15
0
8
0
0
0
% M
% Asn:
0
8
29
0
8
0
8
0
15
0
8
8
8
0
0
% N
% Pro:
0
22
0
15
8
0
8
15
29
8
36
29
15
15
43
% P
% Gln:
15
0
15
0
22
0
8
0
15
0
0
8
0
8
0
% Q
% Arg:
8
0
0
0
0
0
0
0
0
0
0
8
0
0
8
% R
% Ser:
0
0
29
0
0
0
8
0
8
29
8
15
15
36
8
% S
% Thr:
0
0
0
15
36
0
8
0
15
0
8
0
0
8
15
% T
% Val:
0
0
0
0
0
15
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
8
8
8
29
8
15
50
36
8
15
8
8
8
22
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _