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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TAPT1 All Species: 50.61
Human Site: S395 Identified Species: 79.52
UniProt: Q6NXT6 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NXT6 NP_699196.2 567 64260 S395 K N A Y T D Y S D S V A R R M
Chimpanzee Pan troglodytes XP_001161103 567 64298 S395 K N A Y T D Y S D S V A R R M
Rhesus Macaque Macaca mulatta XP_001100596 567 64255 S395 K N A Y T D Y S D S V A R R M
Dog Lupus familis XP_545933 568 64160 S392 K N A Y T D Y S D S V A R R M
Cat Felis silvestris
Mouse Mus musculus Q4VBD2 564 63876 S392 K N A Y T D Y S D S V A R R M
Rat Rattus norvegicus XP_223500 688 78021 S516 K N A Y T D Y S D S V A R R M
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506017 506 56992 A338 T D Y S D S V A R R M G F I P
Chicken Gallus gallus Q5ZLG8 581 65757 S409 K N A Y T D Y S D S V S R R M
Frog Xenopus laevis Q5EAY8 546 61776 S376 K N A C T D Y S D S V S R R M
Zebra Danio Brachydanio rerio A2BIE7 567 64760 S392 K N A Y T D Y S D S V S R R M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9VED0 676 75547 S406 K H A F S D H S D L V A R R M
Honey Bee Apis mellifera XP_396240 216 24620 I52 L V K S Q S V I K L Y I F Y N
Nematode Worm Caenorhab. elegans Q9U3H8 712 80694 S462 Q S A F S D Y S D Q V S R R M
Sea Urchin Strong. purpuratus XP_001180704 1179 132553 S984 K N A F S D H S D L V A R R M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P40085 556 64776 T385 Y K D Y S T R T H K L E D R L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 98.7 92.7 N.A. 95.5 76.3 N.A. 74.9 85.3 79.7 77.9 N.A. 38.4 24.3 35.1 26.6
Protein Similarity: 100 99.8 99.1 94.8 N.A. 97 79.3 N.A. 78.3 91 86.7 85.1 N.A. 56.3 31.9 52.5 36.7
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 0 93.3 86.6 93.3 N.A. 66.6 0 60 73.3
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 100 93.3 100 N.A. 93.3 0 93.3 93.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 24.8 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 45.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 40 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 80 0 0 0 0 7 0 0 0 54 0 0 0 % A
% Cys: 0 0 0 7 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 7 7 0 7 80 0 0 80 0 0 0 7 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % E
% Phe: 0 0 0 20 0 0 0 0 0 0 0 0 14 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % G
% His: 0 7 0 0 0 0 14 0 7 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 7 0 0 0 7 0 7 0 % I
% Lys: 74 7 7 0 0 0 0 0 7 7 0 0 0 0 0 % K
% Leu: 7 0 0 0 0 0 0 0 0 20 7 0 0 0 7 % L
% Met: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 80 % M
% Asn: 0 67 0 0 0 0 0 0 0 0 0 0 0 0 7 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % P
% Gln: 7 0 0 0 7 0 0 0 0 7 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 7 0 7 7 0 0 80 87 0 % R
% Ser: 0 7 0 14 27 14 0 80 0 60 0 27 0 0 0 % S
% Thr: 7 0 0 0 60 7 0 7 0 0 0 0 0 0 0 % T
% Val: 0 7 0 0 0 0 14 0 0 0 80 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 7 60 0 0 67 0 0 0 7 0 0 7 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _