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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
JMJD6
All Species:
29.09
Human Site:
S381
Identified Species:
53.33
UniProt:
Q6NYC1
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NYC1
NP_001074930.1
403
46462
S381
R
K
K
R
R
T
C
S
M
V
G
N
G
D
T
Chimpanzee
Pan troglodytes
XP_001153340
372
43091
S351
S
D
S
S
S
S
S
S
S
S
S
S
D
S
D
Rhesus Macaque
Macaca mulatta
XP_001100530
333
39044
M312
K
K
R
R
T
C
S
M
V
G
N
G
D
T
T
Dog
Lupus familis
XP_849080
403
46510
S381
R
K
K
R
R
T
C
S
M
M
G
N
G
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9ERI5
403
46549
S381
R
K
K
R
R
T
C
S
M
V
G
N
G
D
T
Rat
Rattus norvegicus
Q6AYK2
403
46522
S381
R
K
K
R
R
T
C
S
M
V
G
N
G
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507689
408
46373
S375
R
K
K
R
R
T
C
S
L
V
G
N
G
D
T
Chicken
Gallus gallus
Q5ZMK5
414
47741
S381
R
K
K
R
R
T
C
S
M
M
G
N
G
D
T
Frog
Xenopus laevis
Q6GND3
403
46584
S381
K
K
K
R
K
I
C
S
V
M
E
N
G
D
S
Zebra Danio
Brachydanio rerio
Q6PFM0
403
46669
G381
R
K
K
R
R
T
G
G
M
M
G
N
G
D
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VD28
408
46987
K386
Q
E
S
L
T
A
K
K
K
K
K
R
R
M
A
Honey Bee
Apis mellifera
XP_394543
391
45344
S370
S
E
E
S
A
D
D
S
G
Q
E
S
L
T
T
Nematode Worm
Caenorhab. elegans
Q9GYI4
400
46600
N379
C
G
G
R
K
R
K
N
D
D
R
S
N
E
C
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
90.8
79.1
98.2
N.A.
97.7
98
N.A.
87.2
92.5
84.6
85.1
N.A.
64.9
65.7
50.6
N.A.
Protein Similarity:
100
91.3
81.1
100
N.A.
99.2
99.2
N.A.
89.7
94.9
92
91.8
N.A.
74.7
78.6
66
N.A.
P-Site Identity:
100
6.6
20
93.3
N.A.
100
100
N.A.
93.3
93.3
53.3
73.3
N.A.
0
13.3
6.6
N.A.
P-Site Similarity:
100
20
40
100
N.A.
100
100
N.A.
100
100
86.6
80
N.A.
13.3
33.3
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
8
0
0
0
0
0
0
0
0
8
% A
% Cys:
8
0
0
0
0
8
54
0
0
0
0
0
0
0
8
% C
% Asp:
0
8
0
0
0
8
8
0
8
8
0
0
16
62
8
% D
% Glu:
0
16
8
0
0
0
0
0
0
0
16
0
0
8
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
8
8
0
0
0
8
8
8
8
54
8
62
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% I
% Lys:
16
70
62
0
16
0
16
8
8
8
8
0
0
0
0
% K
% Leu:
0
0
0
8
0
0
0
0
8
0
0
0
8
0
0
% L
% Met:
0
0
0
0
0
0
0
8
47
31
0
0
0
8
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
8
62
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
54
0
8
77
54
8
0
0
0
0
8
8
8
0
0
% R
% Ser:
16
0
16
16
8
8
16
70
8
8
8
24
0
8
8
% S
% Thr:
0
0
0
0
16
54
0
0
0
0
0
0
0
16
62
% T
% Val:
0
0
0
0
0
0
0
0
16
31
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _