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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTRF All Species: 23.94
Human Site: S108 Identified Species: 52.67
UniProt: Q6NZI2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NZI2 NP_036364.2 390 43476 S108 A T T S N T V S K L L E K V R
Chimpanzee Pan troglodytes XP_511507 390 43352 S108 A T T S H T V S K L L E K V R
Rhesus Macaque Macaca mulatta XP_001094944 553 61078 S108 A T T S N T V S K L L E K V R
Dog Lupus familis XP_548089 390 43449 S108 A T T S N T V S K L L E K V R
Cat Felis silvestris
Mouse Mus musculus O54724 392 43935 S110 A T T S N T V S K L L E K V R
Rat Rattus norvegicus P85125 392 43890 S110 A T T S N T V S K L L E K V R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513924 343 39493 K101 R K V S A R V K E V K A R V E
Chicken Gallus gallus NP_001001471 354 40414 T106 K V S V N V K T V R Q N L E K
Frog Xenopus laevis A2VDA9 359 41001 D108 K D V K S R V D K Q S D Q V Q
Zebra Danio Brachydanio rerio A1L260 329 36516 V87 L L Q K A R R V S T H V K E V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RVN0 174 20066
Conservation
Percent
Protein Identity: 100 96.4 68.3 93.8 N.A. 92.5 93.1 N.A. 29.4 72.8 30.5 34.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.9 69.8 95.9 N.A. 95.4 95.1 N.A. 50 80.5 52.5 54.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 93.3 100 100 N.A. 100 100 N.A. 20 6.6 20 6.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 40 26.6 46.6 6.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 20.2
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 29.2
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 0
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 0
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 55 0 0 0 19 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 10 0 0 0 0 0 10 0 0 0 10 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 10 0 0 55 0 19 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 10 0 0 0 0 0 10 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 19 10 0 19 0 0 10 10 64 0 10 0 64 0 10 % K
% Leu: 10 10 0 0 0 0 0 0 0 55 55 0 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 55 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 10 0 0 0 0 0 0 10 10 0 10 0 10 % Q
% Arg: 10 0 0 0 0 28 10 0 0 10 0 0 10 0 55 % R
% Ser: 0 0 10 64 10 0 0 55 10 0 10 0 0 0 0 % S
% Thr: 0 55 55 0 0 55 0 10 0 10 0 0 0 0 0 % T
% Val: 0 10 19 10 0 10 73 10 10 10 0 10 0 73 10 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _