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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PTRF All Species: 29.7
Human Site: T292 Identified Species: 65.33
UniProt: Q6NZI2 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NZI2 NP_036364.2 390 43476 T292 E R R E K L K T S R D K L R K
Chimpanzee Pan troglodytes XP_511507 390 43352 T292 E R R E K L K T S R D K L R K
Rhesus Macaque Macaca mulatta XP_001094944 553 61078 T292 E R R E K L K T S R D K L R K
Dog Lupus familis XP_548089 390 43449 T292 E R R E K L K T S R D K L R K
Cat Felis silvestris
Mouse Mus musculus O54724 392 43935 T294 E R R E K L K T S R D K L R K
Rat Rattus norvegicus P85125 392 43890 T294 E R R E K L K T S R D K L R K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513924 343 39493 F259 A A P N K D T F K M Y I H K K
Chicken Gallus gallus NP_001001471 354 40414 T264 E R R E K M K T S R D K L R K
Frog Xenopus laevis A2VDA9 359 41001 T270 K K K G K Q R T T A E G Q E G
Zebra Danio Brachydanio rerio A1L260 329 36516 E245 I V P P E Q R E K I K Q S S E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa Q7RVN0 174 20066 E90 E R G L K V K E Y E L R K R N
Conservation
Percent
Protein Identity: 100 96.4 68.3 93.8 N.A. 92.5 93.1 N.A. 29.4 72.8 30.5 34.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 96.9 69.8 95.9 N.A. 95.4 95.1 N.A. 50 80.5 52.5 54.3 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 100 N.A. 100 100 N.A. 13.3 93.3 13.3 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 20 100 53.3 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. 20.2
Protein Similarity: N.A. N.A. N.A. N.A. N.A. 29.2
P-Site Identity: N.A. N.A. N.A. N.A. N.A. 33.3
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 10 0 0 0 0 0 0 0 10 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 64 0 0 0 0 % D
% Glu: 73 0 0 64 10 0 0 19 0 10 10 0 0 10 10 % E
% Phe: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 10 10 0 0 0 0 0 0 0 10 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 10 0 10 0 0 0 % I
% Lys: 10 10 10 0 91 0 73 0 19 0 10 64 10 10 73 % K
% Leu: 0 0 0 10 0 55 0 0 0 0 10 0 64 0 0 % L
% Met: 0 0 0 0 0 10 0 0 0 10 0 0 0 0 0 % M
% Asn: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 10 % N
% Pro: 0 0 19 10 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 19 0 0 0 0 0 10 10 0 0 % Q
% Arg: 0 73 64 0 0 0 19 0 0 64 0 10 0 73 0 % R
% Ser: 0 0 0 0 0 0 0 0 64 0 0 0 10 10 0 % S
% Thr: 0 0 0 0 0 0 10 73 10 0 0 0 0 0 0 % T
% Val: 0 10 0 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _