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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
15.45
Human Site:
S414
Identified Species:
26.15
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
S414
F
Q
A
P
G
V
K
S
G
N
K
R
S
S
S
Chimpanzee
Pan troglodytes
XP_509445
540
59236
S253
K
S
G
N
K
R
S
S
S
H
S
S
S
G
S
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
S414
F
Q
T
P
G
V
K
S
S
S
K
R
S
S
S
Dog
Lupus familis
XP_534658
709
78944
S414
F
Q
A
P
S
L
R
S
G
S
K
R
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
S417
Q
S
P
S
M
R
S
S
G
K
R
S
S
S
Q
Rat
Rattus norvegicus
NP_001099399
476
51796
I189
A
S
Y
L
N
S
N
I
Q
S
P
S
V
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
S411
F
Q
S
S
S
P
K
S
S
C
K
R
S
A
S
Chicken
Gallus gallus
Q5F3D1
613
68449
R326
P
S
S
H
H
S
K
R
P
K
D
D
L
E
V
Frog
Xenopus laevis
Q6DD45
743
82926
S399
T
D
S
F
P
P
G
S
S
N
K
S
N
K
R
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
E398
G
S
S
K
R
P
H
E
S
D
S
T
P
Q
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
P266
M
R
V
L
G
Y
P
P
A
W
L
E
E
A
K
Honey Bee
Apis mellifera
XP_001122586
556
62911
I269
S
L
F
N
S
D
G
I
P
V
E
D
P
N
D
Nematode Worm
Caenorhab. elegans
P34656
453
51815
I166
K
H
F
K
P
G
V
I
S
D
R
L
R
A
A
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
N339
N
S
I
P
M
Q
S
N
Q
S
K
E
V
L
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
20
80
73.3
N.A.
26.6
6.6
N.A.
53.3
6.6
20
0
N.A.
6.6
0
0
13.3
P-Site Similarity:
100
26.6
86.6
93.3
N.A.
33.3
13.3
N.A.
66.6
13.3
33.3
13.3
N.A.
20
13.3
26.6
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
15
0
0
0
0
0
8
0
0
0
0
22
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% C
% Asp:
0
8
0
0
0
8
0
0
0
15
8
15
0
0
8
% D
% Glu:
0
0
0
0
0
0
0
8
0
0
8
15
8
8
0
% E
% Phe:
29
0
15
8
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
8
0
8
0
22
8
15
0
22
0
0
0
0
8
0
% G
% His:
0
8
0
8
8
0
8
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
22
0
0
0
0
0
0
0
% I
% Lys:
15
0
0
15
8
0
29
0
0
15
43
0
0
15
22
% K
% Leu:
0
8
0
15
0
8
0
0
0
0
8
8
8
8
0
% L
% Met:
8
0
0
0
15
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
15
8
0
8
8
0
15
0
0
8
8
0
% N
% Pro:
8
0
8
29
15
22
8
8
15
0
8
0
15
0
0
% P
% Gln:
8
29
0
0
0
8
0
0
15
0
0
0
0
8
8
% Q
% Arg:
0
8
0
0
8
15
8
8
0
0
15
29
8
0
8
% R
% Ser:
8
43
29
15
22
15
22
50
43
29
15
29
43
29
43
% S
% Thr:
8
0
8
0
0
0
0
0
0
0
0
8
0
0
0
% T
% Val:
0
0
8
0
0
15
8
0
0
8
0
0
15
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
8
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _