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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
8.48
Human Site:
S591
Identified Species:
14.36
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
S591
P
E
I
F
T
K
K
S
E
A
G
H
A
S
S
Chimpanzee
Pan troglodytes
XP_509445
540
59236
E425
E
I
F
T
K
K
S
E
A
G
H
A
S
S
P
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
S591
P
E
I
F
T
K
K
S
E
A
G
H
A
S
S
Dog
Lupus familis
XP_534658
709
78944
K593
G
P
D
V
C
T
K
K
L
E
V
E
H
S
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
T593
E
P
A
A
S
V
D
T
A
G
P
E
P
S
C
Rat
Rattus norvegicus
NP_001099399
476
51796
L361
R
A
L
E
K
P
V
L
A
E
P
D
T
A
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
T600
T
C
P
Q
I
T
Q
T
E
H
L
Q
S
S
P
Chicken
Gallus gallus
Q5F3D1
613
68449
S498
E
T
K
F
S
S
I
S
E
Q
V
P
E
N
E
Frog
Xenopus laevis
Q6DD45
743
82926
L612
I
P
E
E
G
G
P
L
I
P
E
E
G
G
P
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
E575
P
A
V
S
N
V
C
E
D
E
M
T
D
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
Q438
A
Q
Q
E
E
L
L
Q
E
L
D
V
N
A
S
Honey Bee
Apis mellifera
XP_001122586
556
62911
E441
S
P
S
L
F
E
L
E
N
M
K
K
Q
L
L
Nematode Worm
Caenorhab. elegans
P34656
453
51815
K338
G
S
A
S
T
E
E
K
H
L
L
T
P
I
R
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
K511
D
G
E
L
G
S
D
K
R
T
K
G
R
N
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
13.3
100
13.3
N.A.
6.6
6.6
N.A.
13.3
20
0
6.6
N.A.
13.3
0
6.6
0
P-Site Similarity:
100
20
100
13.3
N.A.
20
20
N.A.
33.3
33.3
0
26.6
N.A.
26.6
6.6
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
15
8
0
0
0
0
22
15
0
8
15
15
0
% A
% Cys:
0
8
0
0
8
0
8
0
0
0
0
0
0
0
8
% C
% Asp:
8
0
8
0
0
0
15
0
8
0
8
8
8
0
0
% D
% Glu:
22
15
15
22
8
15
8
22
36
22
8
22
8
0
8
% E
% Phe:
0
0
8
22
8
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
15
8
0
0
15
8
0
0
0
15
15
8
8
8
8
% G
% His:
0
0
0
0
0
0
0
0
8
8
8
15
8
0
0
% H
% Ile:
8
8
15
0
8
0
8
0
8
0
0
0
0
8
0
% I
% Lys:
0
0
8
0
15
22
22
22
0
0
15
8
0
8
0
% K
% Leu:
0
0
8
15
0
8
15
15
8
15
15
0
0
8
15
% L
% Met:
0
0
0
0
0
0
0
0
0
8
8
0
0
0
0
% M
% Asn:
0
0
0
0
8
0
0
0
8
0
0
0
8
15
0
% N
% Pro:
22
29
8
0
0
8
8
0
0
8
15
8
15
0
22
% P
% Gln:
0
8
8
8
0
0
8
8
0
8
0
8
8
0
0
% Q
% Arg:
8
0
0
0
0
0
0
0
8
0
0
0
8
0
8
% R
% Ser:
8
8
8
15
15
15
8
22
0
0
0
0
15
43
29
% S
% Thr:
8
8
0
8
22
15
0
15
0
8
0
15
8
0
8
% T
% Val:
0
0
8
8
0
15
8
0
0
0
15
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _