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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
9.7
Human Site:
S640
Identified Species:
16.41
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
S640
C
D
I
S
N
G
G
S
Q
K
L
F
P
A
D
Chimpanzee
Pan troglodytes
XP_509445
540
59236
Q474
D
I
S
N
G
G
S
Q
K
L
F
P
A
D
T
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
S640
C
D
V
S
N
G
D
S
R
K
L
F
P
A
D
Dog
Lupus familis
XP_534658
709
78944
S642
C
D
V
S
N
G
G
S
Q
K
L
L
H
V
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
N642
M
N
M
S
N
G
S
N
Q
Q
P
I
H
P
D
Rat
Rattus norvegicus
NP_001099399
476
51796
N410
G
G
V
L
N
I
S
N
G
G
N
H
L
D
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
N649
C
E
V
S
N
G
G
N
E
A
L
A
Q
A
V
Chicken
Gallus gallus
Q5F3D1
613
68449
G547
P
N
H
E
V
N
D
G
E
S
I
V
D
N
K
Frog
Xenopus laevis
Q6DD45
743
82926
S677
N
A
S
E
K
N
P
S
D
E
D
A
T
E
E
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
E624
A
P
Q
K
N
V
Q
E
S
S
S
E
V
A
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
P487
S
R
S
A
P
S
T
P
F
K
A
S
Y
E
G
Honey Bee
Apis mellifera
XP_001122586
556
62911
N490
E
S
N
H
I
R
Q
N
E
L
N
T
S
H
G
Nematode Worm
Caenorhab. elegans
P34656
453
51815
R387
G
I
Q
P
F
E
A
R
E
E
L
T
G
C
K
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
S560
E
A
P
C
L
N
S
S
S
Q
W
I
T
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
6.6
80
73.3
N.A.
33.3
6.6
N.A.
46.6
0
6.6
20
N.A.
6.6
0
6.6
13.3
P-Site Similarity:
100
20
93.3
80
N.A.
60
20
N.A.
73.3
20
20
20
N.A.
13.3
13.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
0
8
0
0
8
0
0
8
8
15
8
29
0
% A
% Cys:
29
0
0
8
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
8
22
0
0
0
0
15
0
8
0
8
0
8
15
43
% D
% Glu:
15
8
0
15
0
8
0
8
29
15
0
8
0
15
8
% E
% Phe:
0
0
0
0
8
0
0
0
8
0
8
15
0
0
0
% F
% Gly:
15
8
0
0
8
43
22
8
8
8
0
0
8
0
15
% G
% His:
0
0
8
8
0
0
0
0
0
0
0
8
15
8
0
% H
% Ile:
0
15
8
0
8
8
0
0
0
0
8
15
0
0
0
% I
% Lys:
0
0
0
8
8
0
0
0
8
29
0
0
0
0
15
% K
% Leu:
0
0
0
8
8
0
0
0
0
15
36
8
8
8
0
% L
% Met:
8
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
15
8
8
50
22
0
29
0
0
15
0
0
8
0
% N
% Pro:
8
8
8
8
8
0
8
8
0
0
8
8
15
8
0
% P
% Gln:
0
0
15
0
0
0
15
8
22
15
0
0
8
0
0
% Q
% Arg:
0
8
0
0
0
8
0
8
8
0
0
0
0
0
0
% R
% Ser:
8
8
22
36
0
8
29
36
15
15
8
8
8
0
0
% S
% Thr:
0
0
0
0
0
0
8
0
0
0
0
15
15
0
15
% T
% Val:
0
0
29
0
8
8
0
0
0
0
0
8
8
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _