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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZCCHC8 All Species: 6.97
Human Site: T547 Identified Species: 11.79
UniProt: Q6NZY4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NZY4 NP_060082.2 707 78577 T547 D S D V P V D T P L T G N S V
Chimpanzee Pan troglodytes XP_509445 540 59236 P381 S D V P V D T P L T G N S V A
Rhesus Macaque Macaca mulatta XP_001099406 707 78532 T547 D S D I P V D T P L T G N S V
Dog Lupus familis XP_534658 709 78944 L549 D I P V D T P L T G N S V V S
Cat Felis silvestris
Mouse Mus musculus Q9CYA6 709 78007 D549 G D S D V P G D T P L T G N S
Rat Rattus norvegicus NP_001099399 476 51796 A317 I W A A L Q Q A E G A N S D S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506640 716 78801 L556 D I P G D T P L T G N S V T S
Chicken Gallus gallus Q5F3D1 613 68449 S454 A E S T N S D S D I P V D T P
Frog Xenopus laevis Q6DD45 743 82926 L584 P R Q T A H E L K S P C V I T
Zebra Danio Brachydanio rerio NP_001077287 692 77048 V531 N S D S D T P V P S S P S V V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q2PE14 553 62387 D394 E L E E E T E D P P L P P S V
Honey Bee Apis mellifera XP_001122586 556 62911 P397 P S E S P L K P P E P P L P Q
Nematode Worm Caenorhab. elegans P34656 453 51815 K294 A K S T P K H K K F A N E D D
Sea Urchin Strong. purpuratus XP_798020 626 69735 T467 P D L D R L M T E R T K L L A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75.1 95.3 87.5 N.A. 80.8 54.5 N.A. 74.8 57.2 55.9 47.8 N.A. 25.8 25.6 22.7 27.4
Protein Similarity: 100 75.2 97.7 92.8 N.A. 88.1 59.2 N.A. 82.8 67.3 69.8 65 N.A. 42.8 42.5 38 45.9
P-Site Identity: 100 0 93.3 13.3 N.A. 0 0 N.A. 6.6 6.6 0 26.6 N.A. 20 20 6.6 13.3
P-Site Similarity: 100 6.6 100 13.3 N.A. 6.6 6.6 N.A. 13.3 33.3 6.6 46.6 N.A. 40 33.3 6.6 20
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 8 8 8 0 0 8 0 0 15 0 0 0 15 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 29 22 22 15 22 8 22 15 8 0 0 0 8 15 8 % D
% Glu: 8 8 15 8 8 0 15 0 15 8 0 0 8 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 8 0 0 8 0 0 8 0 0 22 8 15 8 0 0 % G
% His: 0 0 0 0 0 8 8 0 0 0 0 0 0 0 0 % H
% Ile: 8 15 0 8 0 0 0 0 0 8 0 0 0 8 0 % I
% Lys: 0 8 0 0 0 8 8 8 15 0 0 8 0 0 0 % K
% Leu: 0 8 8 0 8 15 0 22 8 15 15 0 15 8 0 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 8 0 0 0 8 0 0 0 0 0 15 22 15 8 0 % N
% Pro: 22 0 15 8 29 8 22 15 36 15 22 22 8 8 8 % P
% Gln: 0 0 8 0 0 8 8 0 0 0 0 0 0 0 8 % Q
% Arg: 0 8 0 0 8 0 0 0 0 8 0 0 0 0 0 % R
% Ser: 8 29 22 15 0 8 0 8 0 15 8 15 22 22 29 % S
% Thr: 0 0 0 22 0 29 8 22 22 8 22 8 0 15 8 % T
% Val: 0 0 8 15 15 15 0 8 0 0 0 8 22 22 29 % V
% Trp: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _