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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZCCHC8 All Species: 12.73
Human Site: T652 Identified Species: 21.54
UniProt: Q6NZY4 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6NZY4 NP_060082.2 707 78577 T652 P A D T S P S T A T K I H S P
Chimpanzee Pan troglodytes XP_509445 540 59236 A486 A D T S P S M A T K I H S P I
Rhesus Macaque Macaca mulatta XP_001099406 707 78532 T652 P A D T S P S T A T K I H S P
Dog Lupus familis XP_534658 709 78944 T654 H V D T S P S T A T K I H S P
Cat Felis silvestris
Mouse Mus musculus Q9CYA6 709 78007 M654 H P D S R P P M A P K T H S P
Rat Rattus norvegicus NP_001099399 476 51796 A422 L D T R P P T A S K T H S P V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506640 716 78801 L661 Q A V T S T A L P T K I S S P
Chicken Gallus gallus Q5F3D1 613 68449 T559 D N K V V T S T E S S A K N S
Frog Xenopus laevis Q6DD45 743 82926 E689 T E E A A C V E P S P K R S G
Zebra Danio Brachydanio rerio NP_001077287 692 77048 S636 V A D D I E E S G V N K V T F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q2PE14 553 62387 K499 Y E G T P L L K F S V Y D R L
Honey Bee Apis mellifera XP_001122586 556 62911 I502 S H G S V K S I D L G T P V L
Nematode Worm Caenorhab. elegans P34656 453 51815 N399 G C K G N F R N L M D K L K E
Sea Urchin Strong. purpuratus XP_798020 626 69735 S572 T L D S T G D S S V F M S V E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 75.1 95.3 87.5 N.A. 80.8 54.5 N.A. 74.8 57.2 55.9 47.8 N.A. 25.8 25.6 22.7 27.4
Protein Similarity: 100 75.2 97.7 92.8 N.A. 88.1 59.2 N.A. 82.8 67.3 69.8 65 N.A. 42.8 42.5 38 45.9
P-Site Identity: 100 0 100 86.6 N.A. 46.6 6.6 N.A. 53.3 13.3 6.6 13.3 N.A. 6.6 6.6 0 6.6
P-Site Similarity: 100 6.6 100 86.6 N.A. 53.3 20 N.A. 60 26.6 26.6 26.6 N.A. 13.3 13.3 6.6 40
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 29 0 8 8 0 8 15 29 0 0 8 0 0 0 % A
% Cys: 0 8 0 0 0 8 0 0 0 0 0 0 0 0 0 % C
% Asp: 8 15 43 8 0 0 8 0 8 0 8 0 8 0 0 % D
% Glu: 0 15 8 0 0 8 8 8 8 0 0 0 0 0 15 % E
% Phe: 0 0 0 0 0 8 0 0 8 0 8 0 0 0 8 % F
% Gly: 8 0 15 8 0 8 0 0 8 0 8 0 0 0 8 % G
% His: 15 8 0 0 0 0 0 0 0 0 0 15 29 0 0 % H
% Ile: 0 0 0 0 8 0 0 8 0 0 8 29 0 0 8 % I
% Lys: 0 0 15 0 0 8 0 8 0 15 36 22 8 8 0 % K
% Leu: 8 8 0 0 0 8 8 8 8 8 0 0 8 0 15 % L
% Met: 0 0 0 0 0 0 8 8 0 8 0 8 0 0 0 % M
% Asn: 0 8 0 0 8 0 0 8 0 0 8 0 0 8 0 % N
% Pro: 15 8 0 0 22 36 8 0 15 8 8 0 8 15 36 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 8 8 0 8 0 0 0 0 0 8 8 0 % R
% Ser: 8 0 0 29 29 8 36 15 15 22 8 0 29 43 8 % S
% Thr: 15 0 15 36 8 15 8 29 8 29 8 15 0 8 0 % T
% Val: 8 8 8 8 15 0 8 0 0 15 8 0 8 15 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 8 0 0 0 0 0 0 0 0 0 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _