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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
16.06
Human Site:
T654
Identified Species:
27.18
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
T654
D
T
S
P
S
T
A
T
K
I
H
S
P
I
P
Chimpanzee
Pan troglodytes
XP_509445
540
59236
K488
T
S
P
S
M
A
T
K
I
H
S
P
I
P
D
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
T654
D
T
S
P
S
T
A
T
K
I
H
S
P
I
P
Dog
Lupus familis
XP_534658
709
78944
T656
D
T
S
P
S
T
A
T
K
I
H
S
P
V
P
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
P656
D
S
R
P
P
M
A
P
K
T
H
S
P
V
P
Rat
Rattus norvegicus
NP_001099399
476
51796
K424
T
R
P
P
T
A
S
K
T
H
S
P
V
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
T663
V
T
S
T
A
L
P
T
K
I
S
S
P
I
P
Chicken
Gallus gallus
Q5F3D1
613
68449
S561
K
V
V
T
S
T
E
S
S
A
K
N
S
N
P
Frog
Xenopus laevis
Q6DD45
743
82926
S691
E
A
A
C
V
E
P
S
P
K
R
S
G
V
P
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
V638
D
D
I
E
E
S
G
V
N
K
V
T
F
V
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
S501
G
T
P
L
L
K
F
S
V
Y
D
R
L
P
V
Honey Bee
Apis mellifera
XP_001122586
556
62911
L504
G
S
V
K
S
I
D
L
G
T
P
V
L
Q
S
Nematode Worm
Caenorhab. elegans
P34656
453
51815
M401
K
G
N
F
R
N
L
M
D
K
L
K
E
I
R
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
V574
D
S
T
G
D
S
S
V
F
M
S
V
E
E
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
0
100
93.3
N.A.
53.3
6.6
N.A.
60
20
13.3
13.3
N.A.
6.6
6.6
6.6
6.6
P-Site Similarity:
100
6.6
100
100
N.A.
66.6
20
N.A.
66.6
33.3
40
33.3
N.A.
13.3
13.3
13.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
8
8
0
8
15
29
0
0
8
0
0
0
0
0
% A
% Cys:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
43
8
0
0
8
0
8
0
8
0
8
0
0
0
15
% D
% Glu:
8
0
0
8
8
8
8
0
0
0
0
0
15
8
8
% E
% Phe:
0
0
0
8
0
0
8
0
8
0
0
0
8
0
0
% F
% Gly:
15
8
0
8
0
0
8
0
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
15
29
0
0
0
0
% H
% Ile:
0
0
8
0
0
8
0
0
8
29
0
0
8
29
0
% I
% Lys:
15
0
0
8
0
8
0
15
36
22
8
8
0
0
0
% K
% Leu:
0
0
0
8
8
8
8
8
0
0
8
0
15
0
0
% L
% Met:
0
0
0
0
8
8
0
8
0
8
0
0
0
0
0
% M
% Asn:
0
0
8
0
0
8
0
0
8
0
0
8
0
8
0
% N
% Pro:
0
0
22
36
8
0
15
8
8
0
8
15
36
22
58
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% Q
% Arg:
0
8
8
0
8
0
0
0
0
0
8
8
0
0
8
% R
% Ser:
0
29
29
8
36
15
15
22
8
0
29
43
8
0
8
% S
% Thr:
15
36
8
15
8
29
8
29
8
15
0
8
0
0
0
% T
% Val:
8
8
15
0
8
0
0
15
8
0
8
15
8
29
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _