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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
16.67
Human Site:
Y258
Identified Species:
28.21
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
Y258
I
S
E
K
R
K
E
Y
M
D
A
C
G
E
A
Chimpanzee
Pan troglodytes
XP_509445
540
59236
Q101
A
C
G
E
A
N
N
Q
N
F
Q
Q
R
Y
H
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
Y258
I
S
E
K
R
K
E
Y
M
D
A
C
G
E
A
Dog
Lupus familis
XP_534658
709
78944
Y258
I
S
E
K
R
K
E
Y
M
D
A
C
S
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
Y261
I
S
E
K
R
K
E
Y
M
D
A
C
G
E
A
Rat
Rattus norvegicus
NP_001099399
476
51796
K37
N
A
A
R
I
S
E
K
R
K
E
Y
M
D
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
F255
I
S
E
K
R
K
E
F
M
E
A
C
G
E
A
Chicken
Gallus gallus
Q5F3D1
613
68449
H174
Q
N
F
Q
Q
R
Y
H
A
E
E
V
E
E
R
Frog
Xenopus laevis
Q6DD45
743
82926
F244
I
N
M
K
R
K
E
F
L
D
A
C
G
E
A
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
R245
M
A
R
I
N
E
K
R
K
E
F
S
Q
N
N
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
I114
D
N
P
Q
E
L
M
I
S
A
F
E
R
S
R
Honey Bee
Apis mellifera
XP_001122586
556
62911
S117
D
T
D
S
I
S
Q
S
I
E
I
T
T
E
S
Nematode Worm
Caenorhab. elegans
P34656
453
51815
S14
I
E
E
I
Q
P
V
S
L
K
R
K
Q
P
S
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
D187
R
E
C
P
V
A
R
D
L
V
R
I
S
Q
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
0
100
86.6
N.A.
100
13.3
N.A.
86.6
6.6
73.3
0
N.A.
0
6.6
13.3
0
P-Site Similarity:
100
6.6
100
86.6
N.A.
100
33.3
N.A.
100
46.6
93.3
33.3
N.A.
13.3
46.6
33.3
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
15
8
0
8
8
0
0
8
8
43
0
0
0
43
% A
% Cys:
0
8
8
0
0
0
0
0
0
0
0
43
0
0
0
% C
% Asp:
15
0
8
0
0
0
0
8
0
36
0
0
0
8
0
% D
% Glu:
0
15
43
8
8
8
50
0
0
29
15
8
8
58
0
% E
% Phe:
0
0
8
0
0
0
0
15
0
8
15
0
0
0
0
% F
% Gly:
0
0
8
0
0
0
0
0
0
0
0
0
36
0
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
8
% H
% Ile:
50
0
0
15
15
0
0
8
8
0
8
8
0
0
0
% I
% Lys:
0
0
0
43
0
43
8
8
8
15
0
8
0
0
0
% K
% Leu:
0
0
0
0
0
8
0
0
22
0
0
0
0
0
0
% L
% Met:
8
0
8
0
0
0
8
0
36
0
0
0
8
0
0
% M
% Asn:
8
22
0
0
8
8
8
0
8
0
0
0
0
8
15
% N
% Pro:
0
0
8
8
0
8
0
0
0
0
0
0
0
8
0
% P
% Gln:
8
0
0
15
15
0
8
8
0
0
8
8
15
8
0
% Q
% Arg:
8
0
8
8
43
8
8
8
8
0
15
0
15
0
15
% R
% Ser:
0
36
0
8
0
15
0
15
8
0
0
8
15
8
15
% S
% Thr:
0
8
0
0
0
0
0
0
0
0
0
8
8
0
8
% T
% Val:
0
0
0
0
8
0
8
0
0
8
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
8
29
0
0
0
8
0
8
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _