KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZCCHC8
All Species:
25.76
Human Site:
Y685
Identified Species:
43.59
UniProt:
Q6NZY4
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY4
NP_060082.2
707
78577
Y685
M
A
E
S
T
G
M
Y
L
R
I
R
S
L
L
Chimpanzee
Pan troglodytes
XP_509445
540
59236
L519
A
E
S
T
G
M
Y
L
R
I
R
S
L
L
K
Rhesus Macaque
Macaca mulatta
XP_001099406
707
78532
Y685
M
A
E
S
T
G
M
Y
L
R
I
R
S
L
L
Dog
Lupus familis
XP_534658
709
78944
Y687
M
A
E
S
T
G
M
Y
L
R
I
R
N
L
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYA6
709
78007
Y687
M
A
E
S
T
G
M
Y
L
R
I
R
N
L
L
Rat
Rattus norvegicus
NP_001099399
476
51796
L455
A
E
S
T
G
M
Y
L
R
I
R
N
L
L
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506640
716
78801
Y694
M
A
E
S
T
G
V
Y
L
R
I
R
S
L
L
Chicken
Gallus gallus
Q5F3D1
613
68449
G592
E
N
M
T
E
S
T
G
T
Y
L
R
I
R
S
Frog
Xenopus laevis
Q6DD45
743
82926
Y722
M
S
D
S
T
G
V
Y
L
R
L
R
G
L
L
Zebra Danio
Brachydanio rerio
NP_001077287
692
77048
A669
E
F
T
E
V
A
E
A
T
G
V
Y
L
K
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q2PE14
553
62387
Y532
L
P
D
S
T
G
K
Y
E
Q
M
K
D
L
L
Honey Bee
Apis mellifera
XP_001122586
556
62911
E535
I
C
N
V
I
N
Y
E
N
L
P
D
S
T
G
Nematode Worm
Caenorhab. elegans
P34656
453
51815
N432
T
N
E
I
S
S
S
N
N
S
G
T
A
K
N
Sea Urchin
Strong. purpuratus
XP_798020
626
69735
A605
I
A
P
H
D
F
E
A
D
E
P
K
K
K
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
75.1
95.3
87.5
N.A.
80.8
54.5
N.A.
74.8
57.2
55.9
47.8
N.A.
25.8
25.6
22.7
27.4
Protein Similarity:
100
75.2
97.7
92.8
N.A.
88.1
59.2
N.A.
82.8
67.3
69.8
65
N.A.
42.8
42.5
38
45.9
P-Site Identity:
100
6.6
100
93.3
N.A.
93.3
6.6
N.A.
93.3
6.6
66.6
0
N.A.
40
6.6
6.6
6.6
P-Site Similarity:
100
13.3
100
100
N.A.
100
13.3
N.A.
100
20
93.3
13.3
N.A.
73.3
13.3
20
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
43
0
0
0
8
0
15
0
0
0
0
8
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
15
0
8
0
0
0
8
0
0
8
8
0
0
% D
% Glu:
15
15
43
8
8
0
15
8
8
8
0
0
0
0
0
% E
% Phe:
0
8
0
0
0
8
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
15
50
0
8
0
8
8
0
8
0
15
% G
% His:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
0
0
8
8
0
0
0
0
15
36
0
8
0
8
% I
% Lys:
0
0
0
0
0
0
8
0
0
0
0
15
8
22
15
% K
% Leu:
8
0
0
0
0
0
0
15
43
8
15
0
22
65
50
% L
% Met:
43
0
8
0
0
15
29
0
0
0
8
0
0
0
0
% M
% Asn:
0
15
8
0
0
8
0
8
15
0
0
8
15
0
8
% N
% Pro:
0
8
8
0
0
0
0
0
0
0
15
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
15
43
15
50
0
8
0
% R
% Ser:
0
8
15
50
8
15
8
0
0
8
0
8
29
0
8
% S
% Thr:
8
0
8
22
50
0
8
0
15
0
0
8
0
8
0
% T
% Val:
0
0
0
8
8
0
15
0
0
0
8
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
22
50
0
8
0
8
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _