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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC42EP5
All Species:
35.45
Human Site:
T46
Identified Species:
86.67
UniProt:
Q6NZY7
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6NZY7
NP_659494.2
148
15207
T46
G
G
D
A
F
G
D
T
S
F
L
S
R
H
G
Chimpanzee
Pan troglodytes
XP_001174977
148
15249
T46
G
G
D
A
F
G
D
T
S
F
L
S
R
H
G
Rhesus Macaque
Macaca mulatta
XP_001087677
356
38026
T50
A
G
D
A
F
G
D
T
S
F
L
N
S
K
A
Dog
Lupus familis
XP_854183
153
15808
T46
G
G
D
A
F
G
D
T
S
F
L
S
R
H
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9Z0X0
150
15526
T46
G
G
D
A
F
G
D
T
S
F
L
S
R
H
G
Rat
Rattus norvegicus
A1A5P0
388
41010
T61
G
G
D
V
F
G
D
T
S
F
L
S
N
H
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521534
374
39662
T50
A
G
D
A
F
G
D
T
S
F
L
H
S
K
A
Chicken
Gallus gallus
XP_001233620
302
32279
T50
A
G
D
A
F
G
D
T
S
F
L
T
S
K
A
Frog
Xenopus laevis
NP_001087849
306
33197
T45
G
G
D
V
F
G
D
T
S
F
L
S
N
H
G
Zebra Danio
Brachydanio rerio
NP_001039311
295
32631
T40
G
G
D
A
F
G
D
T
S
F
L
S
S
H
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
25.8
83.6
N.A.
79.3
25.5
N.A.
25.6
30.1
27.4
25.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
30.6
87.5
N.A.
82.6
30.1
N.A.
28.8
37.4
34.3
32.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
66.6
100
N.A.
100
86.6
N.A.
66.6
66.6
86.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
73.3
100
N.A.
100
86.6
N.A.
66.6
73.3
86.6
93.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
30
0
0
80
0
0
0
0
0
0
0
0
0
0
30
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
100
0
0
0
100
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
100
0
0
0
0
100
0
0
0
0
0
% F
% Gly:
70
100
0
0
0
100
0
0
0
0
0
0
0
0
70
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
10
0
70
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
0
30
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
0
100
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
10
20
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
100
0
0
70
40
0
0
% S
% Thr:
0
0
0
0
0
0
0
100
0
0
0
10
0
0
0
% T
% Val:
0
0
0
20
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _