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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KNL2 All Species: 5.45
Human Site: T545 Identified Species: 24
UniProt: Q6P0N0 Number Species: 5
    Phosphosite Substitution
    Charge Score: -0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P0N0 NP_060823.3 1132 129085 T545 H S E S P G A T E L N M C H S
Chimpanzee Pan troglodytes XP_522841 1132 129154 T545 H S E S P G A T E L N M C H S
Rhesus Macaque Macaca mulatta
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q80WQ8 998 113937 T439 R A E K K N K T R Q E T A R V
Rat Rattus norvegicus NP_001103001 990 113282 R430 D D F L E Q L R A E E K N K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514689 921 104015 H362 K T P S S L S H T D A K K V S
Chicken Gallus gallus XP_421481 1085 121843 P509 D E H T Y Q T P K H K P I L N
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 N.A. N.A. N.A. 49 50 N.A. 29.1 29.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.4 N.A. N.A. N.A. 64.3 64.6 N.A. 46 46.2 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 N.A. N.A. N.A. 13.3 0 N.A. 13.3 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 N.A. N.A. N.A. 20 6.6 N.A. 26.6 20 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 17 0 0 0 0 34 0 17 0 17 0 17 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 34 0 0 % C
% Asp: 34 17 0 0 0 0 0 0 0 17 0 0 0 0 0 % D
% Glu: 0 17 50 0 17 0 0 0 34 17 34 0 0 0 0 % E
% Phe: 0 0 17 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 34 0 0 0 0 0 0 0 0 0 % G
% His: 34 0 17 0 0 0 0 17 0 17 0 0 0 34 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 17 0 0 % I
% Lys: 17 0 0 17 17 0 17 0 17 0 17 34 17 17 0 % K
% Leu: 0 0 0 17 0 17 17 0 0 34 0 0 0 17 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 34 0 0 0 % M
% Asn: 0 0 0 0 0 17 0 0 0 0 34 0 17 0 34 % N
% Pro: 0 0 17 0 34 0 0 17 0 0 0 17 0 0 0 % P
% Gln: 0 0 0 0 0 34 0 0 0 17 0 0 0 0 0 % Q
% Arg: 17 0 0 0 0 0 0 17 17 0 0 0 0 17 0 % R
% Ser: 0 34 0 50 17 0 17 0 0 0 0 0 0 0 50 % S
% Thr: 0 17 0 17 0 0 17 50 17 0 0 17 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 17 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 17 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _