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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX57 All Species: 10.3
Human Site: S1036 Identified Species: 20.61
UniProt: Q6P158 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P158 NP_945314.1 1386 155604 S1036 H T D S L R A S K I R L R D L
Chimpanzee Pan troglodytes Q7YR39 1044 119631 R731 Q R A G R A G R V A A G K C F
Rhesus Macaque Macaca mulatta XP_001102912 1320 149221 L986 A L T P D E K L T P L G Y H L
Dog Lupus familis XP_540155 1382 155439 S1032 H T D S L R A S K I R L R D L
Cat Felis silvestris
Mouse Mus musculus Q6P5D3 1388 155744 S1038 H I D S L R A S K V R L R D L
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521356 483 53990 F170 R I G K L M L F G T I F R C L
Chicken Gallus gallus Q5ZI74 1231 137685 A918 T T L G K R L A Q I S T D P R
Frog Xenopus laevis A3KMI0 1362 153300 M1045 L Q V I S N A M S L L R K I G
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P24785 1293 143643 F976 D L L Q Q A G F P E E C M I S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001179903 988 110999 E675 K V F S R L L E P P K N E N I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 E855 K C Y R L Y T E S A Y R N E M
Baker's Yeast Sacchar. cerevisiae Q06698 1435 163026 S1098 D I S V L L V S I L G I G V L
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.8 93.2 92.5 N.A. 86.8 N.A. N.A. 32.1 27 31.6 N.A. N.A. 29.7 N.A. N.A. 40.3
Protein Similarity: 100 41.2 94.1 95.9 N.A. 92.7 N.A. N.A. 33.6 45.8 52.1 N.A. N.A. 46.2 N.A. N.A. 55
P-Site Identity: 100 0 6.6 100 N.A. 86.6 N.A. N.A. 20 20 6.6 N.A. N.A. 0 N.A. N.A. 6.6
P-Site Similarity: 100 6.6 6.6 100 N.A. 93.3 N.A. N.A. 20 33.3 20 N.A. N.A. 0 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 24 24.8 N.A.
Protein Similarity: N.A. N.A. N.A. 41.3 46.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 20 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 0 9 0 0 17 34 9 0 17 9 0 0 0 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 9 0 17 0 % C
% Asp: 17 0 25 0 9 0 0 0 0 0 0 0 9 25 0 % D
% Glu: 0 0 0 0 0 9 0 17 0 9 9 0 9 9 0 % E
% Phe: 0 0 9 0 0 0 0 17 0 0 0 9 0 0 9 % F
% Gly: 0 0 9 17 0 0 17 0 9 0 9 17 9 0 9 % G
% His: 25 0 0 0 0 0 0 0 0 0 0 0 0 9 0 % H
% Ile: 0 25 0 9 0 0 0 0 9 25 9 9 0 17 9 % I
% Lys: 17 0 0 9 9 0 9 0 25 0 9 0 17 0 0 % K
% Leu: 9 17 17 0 50 17 25 9 0 17 17 25 0 0 50 % L
% Met: 0 0 0 0 0 9 0 9 0 0 0 0 9 0 9 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 9 9 9 0 % N
% Pro: 0 0 0 9 0 0 0 0 17 17 0 0 0 9 0 % P
% Gln: 9 9 0 9 9 0 0 0 9 0 0 0 0 0 0 % Q
% Arg: 9 9 0 9 17 34 0 9 0 0 25 17 34 0 9 % R
% Ser: 0 0 9 34 9 0 0 34 17 0 9 0 0 0 9 % S
% Thr: 9 25 9 0 0 0 9 0 9 9 0 9 0 0 0 % T
% Val: 0 9 9 9 0 0 9 0 9 9 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 9 0 0 0 0 9 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _