KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX57
All Species:
7.88
Human Site:
S288
Identified Species:
15.76
UniProt:
Q6P158
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P158
NP_945314.1
1386
155604
S288
L
T
S
R
F
R
K
S
K
P
K
E
S
T
K
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
A27
G
L
S
E
R
H
V
A
Q
F
L
I
G
T
A
Rhesus Macaque
Macaca mulatta
XP_001102912
1320
149221
D274
R
I
E
R
S
V
D
D
S
H
L
N
A
N
E
Dog
Lupus familis
XP_540155
1382
155439
S283
L
T
S
K
F
C
K
S
K
Q
K
E
S
T
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5D3
1388
155744
S288
L
T
N
K
F
C
K
S
K
Q
K
E
S
S
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521356
483
53990
Chicken
Gallus gallus
Q5ZI74
1231
137685
E214
D
D
P
I
Q
P
M
E
Q
G
R
M
P
K
A
Frog
Xenopus laevis
A3KMI0
1362
153300
A288
D
K
Q
G
Q
K
E
A
Q
E
R
I
R
G
Y
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24785
1293
143643
I272
V
K
L
S
P
N
L
I
N
K
I
D
E
V
I
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179903
988
110999
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
R151
R
N
R
D
R
D
D
R
R
D
R
H
R
D
R
Baker's Yeast
Sacchar. cerevisiae
Q06698
1435
163026
D343
L
F
N
L
P
E
D
D
L
P
P
F
F
H
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.8
93.2
92.5
N.A.
86.8
N.A.
N.A.
32.1
27
31.6
N.A.
N.A.
29.7
N.A.
N.A.
40.3
Protein Similarity:
100
41.2
94.1
95.9
N.A.
92.7
N.A.
N.A.
33.6
45.8
52.1
N.A.
N.A.
46.2
N.A.
N.A.
55
P-Site Identity:
100
13.3
6.6
80
N.A.
66.6
N.A.
N.A.
0
0
0
N.A.
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
26.6
20
86.6
N.A.
86.6
N.A.
N.A.
0
13.3
33.3
N.A.
N.A.
13.3
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.3
46.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
17
0
0
0
0
9
0
17
% A
% Cys:
0
0
0
0
0
17
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
9
0
9
0
9
25
17
0
9
0
9
0
9
0
% D
% Glu:
0
0
9
9
0
9
9
9
0
9
0
25
9
0
9
% E
% Phe:
0
9
0
0
25
0
0
0
0
9
0
9
9
0
0
% F
% Gly:
9
0
0
9
0
0
0
0
0
9
0
0
9
9
0
% G
% His:
0
0
0
0
0
9
0
0
0
9
0
9
0
9
0
% H
% Ile:
0
9
0
9
0
0
0
9
0
0
9
17
0
0
9
% I
% Lys:
0
17
0
17
0
9
25
0
25
9
25
0
0
9
34
% K
% Leu:
34
9
9
9
0
0
9
0
9
0
17
0
0
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% M
% Asn:
0
9
17
0
0
9
0
0
9
0
0
9
0
9
0
% N
% Pro:
0
0
9
0
17
9
0
0
0
17
9
0
9
0
0
% P
% Gln:
0
0
9
0
17
0
0
0
25
17
0
0
0
0
0
% Q
% Arg:
17
0
9
17
17
9
0
9
9
0
25
0
17
0
9
% R
% Ser:
0
0
25
9
9
0
0
25
9
0
0
0
25
9
0
% S
% Thr:
0
25
0
0
0
0
0
0
0
0
0
0
0
25
0
% T
% Val:
9
0
0
0
0
9
9
0
0
0
0
0
0
9
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _