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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX57 All Species: 1.82
Human Site: S480 Identified Species: 3.64
UniProt: Q6P158 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P158 NP_945314.1 1386 155604 S480 K A S E S E E S D E D D G P A
Chimpanzee Pan troglodytes Q7YR39 1044 119631 R214 A Y E E A Q K R L K M A E E D
Rhesus Macaque Macaca mulatta XP_001102912 1320 149221 M461 K I C K Q F R M K Q A S R Q F
Dog Lupus familis XP_540155 1382 155439 E475 K E S E P E E E T D E D E G P
Cat Felis silvestris
Mouse Mus musculus Q6P5D3 1388 155744 D480 R L S E L E E D A D E D E G P
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521356 483 53990
Chicken Gallus gallus Q5ZI74 1231 137685 T401 H I K V P E A T L R K I E N Y
Frog Xenopus laevis A3KMI0 1362 153300 K477 K Q V Q E Q N K T E S N K P R
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P24785 1293 143643 E459 R V A R E R C E Q L G D T V G
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001179903 988 110999 D158 A L E Q L Y K D L C N N Y A I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 S338 E E N D V A P S R R P L K K M
Baker's Yeast Sacchar. cerevisiae Q06698 1435 163026 N534 N I S K I I D N P G P L I P D
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.8 93.2 92.5 N.A. 86.8 N.A. N.A. 32.1 27 31.6 N.A. N.A. 29.7 N.A. N.A. 40.3
Protein Similarity: 100 41.2 94.1 95.9 N.A. 92.7 N.A. N.A. 33.6 45.8 52.1 N.A. N.A. 46.2 N.A. N.A. 55
P-Site Identity: 100 6.6 6.6 40 N.A. 33.3 N.A. N.A. 0 6.6 20 N.A. N.A. 6.6 N.A. N.A. 0
P-Site Similarity: 100 33.3 20 53.3 N.A. 53.3 N.A. N.A. 0 13.3 40 N.A. N.A. 20 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 24 24.8 N.A.
Protein Similarity: N.A. N.A. N.A. 41.3 46.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 17 9 9 0 9 9 9 0 9 0 9 9 0 9 9 % A
% Cys: 0 0 9 0 0 0 9 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 9 17 9 17 9 34 0 0 17 % D
% Glu: 9 17 17 34 17 34 25 17 0 17 17 0 34 9 0 % E
% Phe: 0 0 0 0 0 9 0 0 0 0 0 0 0 0 9 % F
% Gly: 0 0 0 0 0 0 0 0 0 9 9 0 9 17 9 % G
% His: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 25 0 0 9 9 0 0 0 0 0 9 9 0 9 % I
% Lys: 34 0 9 17 0 0 17 9 9 9 9 0 17 9 0 % K
% Leu: 0 17 0 0 17 0 0 0 25 9 0 17 0 0 0 % L
% Met: 0 0 0 0 0 0 0 9 0 0 9 0 0 0 9 % M
% Asn: 9 0 9 0 0 0 9 9 0 0 9 17 0 9 0 % N
% Pro: 0 0 0 0 17 0 9 0 9 0 17 0 0 25 17 % P
% Gln: 0 9 0 17 9 17 0 0 9 9 0 0 0 9 0 % Q
% Arg: 17 0 0 9 0 9 9 9 9 17 0 0 9 0 9 % R
% Ser: 0 0 34 0 9 0 0 17 0 0 9 9 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 9 17 0 0 0 9 0 0 % T
% Val: 0 9 9 9 9 0 0 0 0 0 0 0 0 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 9 0 0 0 9 0 0 0 0 0 0 9 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _