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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX57
All Species:
10.61
Human Site:
S636
Identified Species:
21.21
UniProt:
Q6P158
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P158
NP_945314.1
1386
155604
S636
I
R
L
E
S
V
K
S
S
A
T
R
L
L
Y
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
I366
V
L
E
E
E
E
T
I
E
F
V
R
A
T
Q
Rhesus Macaque
Macaca mulatta
XP_001102912
1320
149221
L615
T
E
E
S
D
F
L
L
L
V
L
K
D
I
V
Dog
Lupus familis
XP_540155
1382
155439
S632
I
R
L
E
S
V
K
S
S
A
T
R
L
L
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5D3
1388
155744
S637
I
R
L
E
S
V
K
S
S
A
T
R
L
L
Y
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521356
483
53990
Chicken
Gallus gallus
Q5ZI74
1231
137685
P553
R
V
A
Q
E
L
G
P
N
M
R
K
N
V
G
Frog
Xenopus laevis
A3KMI0
1362
153300
G664
I
R
M
E
S
R
T
G
E
A
T
R
L
L
Y
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24785
1293
143643
Y611
K
D
E
A
E
I
N
Y
N
K
V
C
E
D
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179903
988
110999
S310
D
P
V
L
S
G
V
S
H
V
I
V
D
E
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
K490
A
Y
D
M
P
E
W
K
K
D
A
F
G
K
T
Baker's Yeast
Sacchar. cerevisiae
Q06698
1435
163026
K697
I
R
G
V
N
K
T
K
A
S
T
R
I
K
F
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.8
93.2
92.5
N.A.
86.8
N.A.
N.A.
32.1
27
31.6
N.A.
N.A.
29.7
N.A.
N.A.
40.3
Protein Similarity:
100
41.2
94.1
95.9
N.A.
92.7
N.A.
N.A.
33.6
45.8
52.1
N.A.
N.A.
46.2
N.A.
N.A.
55
P-Site Identity:
100
13.3
0
100
N.A.
100
N.A.
N.A.
0
0
66.6
N.A.
N.A.
0
N.A.
N.A.
13.3
P-Site Similarity:
100
20
13.3
100
N.A.
100
N.A.
N.A.
0
33.3
73.3
N.A.
N.A.
13.3
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.3
46.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
9
0
0
0
0
9
34
9
0
9
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% C
% Asp:
9
9
9
0
9
0
0
0
0
9
0
0
17
9
0
% D
% Glu:
0
9
25
42
25
17
0
0
17
0
0
0
9
9
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
9
0
9
0
0
9
% F
% Gly:
0
0
9
0
0
9
9
9
0
0
0
0
9
0
9
% G
% His:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% H
% Ile:
42
0
0
0
0
9
0
9
0
0
9
0
9
9
0
% I
% Lys:
9
0
0
0
0
9
25
17
9
9
0
17
0
17
9
% K
% Leu:
0
9
25
9
0
9
9
9
9
0
9
0
34
34
0
% L
% Met:
0
0
9
9
0
0
0
0
0
9
0
0
0
0
0
% M
% Asn:
0
0
0
0
9
0
9
0
17
0
0
0
9
0
0
% N
% Pro:
0
9
0
0
9
0
0
9
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
9
% Q
% Arg:
9
42
0
0
0
9
0
0
0
0
9
50
0
0
0
% R
% Ser:
0
0
0
9
42
0
0
34
25
9
0
0
0
0
0
% S
% Thr:
9
0
0
0
0
0
25
0
0
0
42
0
0
9
9
% T
% Val:
9
9
9
9
0
25
9
0
0
17
17
9
0
9
17
% V
% Trp:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
0
% W
% Tyr:
0
9
0
0
0
0
0
9
0
0
0
0
0
0
34
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _