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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX57
All Species:
8.48
Human Site:
T282
Identified Species:
16.97
UniProt:
Q6P158
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P158
NP_945314.1
1386
155604
T282
G
L
E
L
E
Y
L
T
S
R
F
R
K
S
K
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
L21
E
L
H
S
V
L
G
L
S
E
R
H
V
A
Q
Rhesus Macaque
Macaca mulatta
XP_001102912
1320
149221
I268
P
N
Q
I
V
G
R
I
E
R
S
V
D
D
S
Dog
Lupus familis
XP_540155
1382
155439
T277
G
L
E
L
E
Y
L
T
S
K
F
C
K
S
K
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5D3
1388
155744
T282
G
L
E
L
D
Y
L
T
N
K
F
C
K
S
K
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521356
483
53990
Chicken
Gallus gallus
Q5ZI74
1231
137685
D208
W
R
R
M
E
P
D
D
P
I
Q
P
M
E
Q
Frog
Xenopus laevis
A3KMI0
1362
153300
K282
A
T
K
Q
D
K
D
K
Q
G
Q
K
E
A
Q
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24785
1293
143643
K266
Q
L
K
P
Y
P
V
K
L
S
P
N
L
I
N
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179903
988
110999
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
N145
R
D
R
D
R
D
R
N
R
D
R
D
D
R
R
Baker's Yeast
Sacchar. cerevisiae
Q06698
1435
163026
F337
D
P
L
S
F
L
L
F
N
L
P
E
D
D
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.8
93.2
92.5
N.A.
86.8
N.A.
N.A.
32.1
27
31.6
N.A.
N.A.
29.7
N.A.
N.A.
40.3
Protein Similarity:
100
41.2
94.1
95.9
N.A.
92.7
N.A.
N.A.
33.6
45.8
52.1
N.A.
N.A.
46.2
N.A.
N.A.
55
P-Site Identity:
100
13.3
6.6
86.6
N.A.
73.3
N.A.
N.A.
0
6.6
0
N.A.
N.A.
6.6
N.A.
N.A.
0
P-Site Similarity:
100
26.6
20
93.3
N.A.
93.3
N.A.
N.A.
0
20
40
N.A.
N.A.
20
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.3
46.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
0
0
0
0
0
0
17
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
17
0
0
0
% C
% Asp:
9
9
0
9
17
9
17
9
0
9
0
9
25
17
0
% D
% Glu:
9
0
25
0
25
0
0
0
9
9
0
9
9
9
0
% E
% Phe:
0
0
0
0
9
0
0
9
0
0
25
0
0
0
0
% F
% Gly:
25
0
0
0
0
9
9
0
0
9
0
0
0
0
0
% G
% His:
0
0
9
0
0
0
0
0
0
0
0
9
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
9
0
9
0
0
0
9
0
% I
% Lys:
0
0
17
0
0
9
0
17
0
17
0
9
25
0
25
% K
% Leu:
0
42
9
25
0
17
34
9
9
9
0
0
9
0
9
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
0
9
0
0
% M
% Asn:
0
9
0
0
0
0
0
9
17
0
0
9
0
0
9
% N
% Pro:
9
9
0
9
0
17
0
0
9
0
17
9
0
0
0
% P
% Gln:
9
0
9
9
0
0
0
0
9
0
17
0
0
0
25
% Q
% Arg:
9
9
17
0
9
0
17
0
9
17
17
9
0
9
9
% R
% Ser:
0
0
0
17
0
0
0
0
25
9
9
0
0
25
9
% S
% Thr:
0
9
0
0
0
0
0
25
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
17
0
9
0
0
0
0
9
9
0
0
% V
% Trp:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
25
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _