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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX57
All Species:
8.48
Human Site:
T399
Identified Species:
16.97
UniProt:
Q6P158
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P158
NP_945314.1
1386
155604
T399
F
L
Y
D
K
A
L
T
F
A
E
T
S
E
P
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
E133
K
H
L
R
K
K
R
E
E
E
E
E
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001102912
1320
149221
T380
V
L
P
V
P
S
R
T
R
I
N
N
P
A
C
Dog
Lupus familis
XP_540155
1382
155439
T394
F
L
Y
G
K
A
L
T
F
A
E
T
S
E
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5D3
1388
155744
E399
F
L
Y
G
K
A
L
E
F
A
K
T
S
E
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521356
483
53990
Chicken
Gallus gallus
Q5ZI74
1231
137685
T320
M
Q
F
R
T
V
G
T
K
T
K
I
C
K
L
Frog
Xenopus laevis
A3KMI0
1362
153300
E396
K
S
P
N
P
S
F
E
K
V
P
V
G
K
Y
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24785
1293
143643
L378
D
N
E
Y
R
Q
F
L
E
F
R
E
K
L
P
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179903
988
110999
S77
E
E
L
D
Y
D
T
S
R
H
F
W
T
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
K257
T
R
R
V
D
K
A
K
E
F
V
K
R
D
M
Baker's Yeast
Sacchar. cerevisiae
Q06698
1435
163026
T453
A
K
E
D
S
H
Y
T
L
N
L
I
E
K
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.8
93.2
92.5
N.A.
86.8
N.A.
N.A.
32.1
27
31.6
N.A.
N.A.
29.7
N.A.
N.A.
40.3
Protein Similarity:
100
41.2
94.1
95.9
N.A.
92.7
N.A.
N.A.
33.6
45.8
52.1
N.A.
N.A.
46.2
N.A.
N.A.
55
P-Site Identity:
100
20
13.3
93.3
N.A.
80
N.A.
N.A.
0
6.6
0
N.A.
N.A.
6.6
N.A.
N.A.
6.6
P-Site Similarity:
100
20
20
93.3
N.A.
86.6
N.A.
N.A.
0
26.6
20
N.A.
N.A.
13.3
N.A.
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.3
46.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
20
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
25
9
0
0
25
0
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
9
% C
% Asp:
9
0
0
25
9
9
0
0
0
0
0
0
0
17
9
% D
% Glu:
9
9
17
0
0
0
0
25
25
9
25
17
17
34
9
% E
% Phe:
25
0
9
0
0
0
17
0
25
17
9
0
0
0
0
% F
% Gly:
0
0
0
17
0
0
9
0
0
0
0
0
9
0
0
% G
% His:
0
9
0
0
0
9
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
17
0
0
0
% I
% Lys:
17
9
0
0
34
17
0
9
17
0
17
9
9
25
0
% K
% Leu:
0
34
17
0
0
0
25
9
9
0
9
0
0
9
17
% L
% Met:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
9
% M
% Asn:
0
9
0
9
0
0
0
0
0
9
9
9
0
0
0
% N
% Pro:
0
0
17
0
17
0
0
0
0
0
9
0
9
0
34
% P
% Gln:
0
9
0
0
0
9
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
9
9
17
9
0
17
0
17
0
9
0
9
0
0
% R
% Ser:
0
9
0
0
9
17
0
9
0
0
0
0
25
0
0
% S
% Thr:
9
0
0
0
9
0
9
42
0
9
0
25
9
0
0
% T
% Val:
9
0
0
17
0
9
0
0
0
9
9
9
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
9
0
0
0
% W
% Tyr:
0
0
25
9
9
0
9
0
0
0
0
0
0
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _