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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DHX57 All Species: 15.45
Human Site: Y1283 Identified Species: 30.91
UniProt: Q6P158 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P158 NP_945314.1 1386 155604 Y1283 F D S P Y L L Y H E K I K T S
Chimpanzee Pan troglodytes Q7YR39 1044 119631 S960 H T A R L T R S G Y R T V K Q
Rhesus Macaque Macaca mulatta XP_001102912 1320 149221 Y1217 F D S P Y L L Y H E K I K T S
Dog Lupus familis XP_540155 1382 155439 Y1279 F D S P Y L V Y H E K I K T S
Cat Felis silvestris
Mouse Mus musculus Q6P5D3 1388 155744 Y1285 F D S P Y L L Y H E K I K T S
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521356 483 53990 V399 R D C S M V S V Y P L V L F G
Chicken Gallus gallus Q5ZI74 1231 137685 D1147 L A V L L M T D T D I H V R D
Frog Xenopus laevis A3KMI0 1362 153300 K1275 Q E K V K Y S K V F L R E T T
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P24785 1293 143643 Y1205 G R T F G G G Y G N N G G G Y
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001179903 988 110999 F52 P K A Q E I K F K T K D D G Y
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q38953 1168 134139 Y1084 L V E N Q P V Y I H P S S A L
Baker's Yeast Sacchar. cerevisiae Q06698 1435 163026 F1329 V K Y P F V L F T T S Q V T N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 25.8 93.2 92.5 N.A. 86.8 N.A. N.A. 32.1 27 31.6 N.A. N.A. 29.7 N.A. N.A. 40.3
Protein Similarity: 100 41.2 94.1 95.9 N.A. 92.7 N.A. N.A. 33.6 45.8 52.1 N.A. N.A. 46.2 N.A. N.A. 55
P-Site Identity: 100 0 100 93.3 N.A. 100 N.A. N.A. 6.6 0 6.6 N.A. N.A. 6.6 N.A. N.A. 6.6
P-Site Similarity: 100 13.3 100 100 N.A. 100 N.A. N.A. 26.6 13.3 26.6 N.A. N.A. 13.3 N.A. N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. 24 24.8 N.A.
Protein Similarity: N.A. N.A. N.A. 41.3 46.5 N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 20 N.A.
P-Site Similarity: N.A. N.A. N.A. 13.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 17 0 0 0 0 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 42 0 0 0 0 0 9 0 9 0 9 9 0 9 % D
% Glu: 0 9 9 0 9 0 0 0 0 34 0 0 9 0 0 % E
% Phe: 34 0 0 9 9 0 0 17 0 9 0 0 0 9 0 % F
% Gly: 9 0 0 0 9 9 9 0 17 0 0 9 9 17 9 % G
% His: 9 0 0 0 0 0 0 0 34 9 0 9 0 0 0 % H
% Ile: 0 0 0 0 0 9 0 0 9 0 9 34 0 0 0 % I
% Lys: 0 17 9 0 9 0 9 9 9 0 42 0 34 9 0 % K
% Leu: 17 0 0 9 17 34 34 0 0 0 17 0 9 0 9 % L
% Met: 0 0 0 0 9 9 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 9 0 0 0 0 0 9 9 0 0 0 9 % N
% Pro: 9 0 0 42 0 9 0 0 0 9 9 0 0 0 0 % P
% Gln: 9 0 0 9 9 0 0 0 0 0 0 9 0 0 9 % Q
% Arg: 9 9 0 9 0 0 9 0 0 0 9 9 0 9 0 % R
% Ser: 0 0 34 9 0 0 17 9 0 0 9 9 9 0 34 % S
% Thr: 0 9 9 0 0 9 9 0 17 17 0 9 0 50 9 % T
% Val: 9 9 9 9 0 17 17 9 9 0 0 9 25 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 34 9 0 50 9 9 0 0 0 0 17 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _