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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DHX57
All Species:
9.7
Human Site:
Y741
Identified Species:
19.39
UniProt:
Q6P158
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P158
NP_945314.1
1386
155604
Y741
D
A
I
A
V
T
R
Y
V
L
Q
D
G
S
P
Chimpanzee
Pan troglodytes
Q7YR39
1044
119631
E471
V
A
A
R
V
A
R
E
M
G
V
K
L
G
N
Rhesus Macaque
Macaca mulatta
XP_001102912
1320
149221
Q720
L
S
L
H
L
Q
D
Q
D
S
V
K
D
A
V
Dog
Lupus familis
XP_540155
1382
155439
Y737
D
A
I
A
V
T
R
Y
V
L
Q
D
G
S
P
Cat
Felis silvestris
Mouse
Mus musculus
Q6P5D3
1388
155744
Y742
D
A
L
A
V
T
R
Y
V
L
Q
D
G
S
P
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521356
483
53990
Chicken
Gallus gallus
Q5ZI74
1231
137685
F658
P
V
V
K
V
P
G
F
M
Y
P
V
K
E
Y
Frog
Xenopus laevis
A3KMI0
1362
153300
F769
D
V
V
E
A
T
G
F
V
L
E
Q
D
S
E
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P24785
1293
143643
S716
G
V
T
K
I
I
L
S
T
N
I
A
E
T
S
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001179903
988
110999
M415
S
E
A
S
A
R
A
M
G
K
V
R
Y
D
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q38953
1168
134139
A595
L
G
E
E
V
G
Y
A
I
R
F
E
D
C
T
Baker's Yeast
Sacchar. cerevisiae
Q06698
1435
163026
F802
D
I
L
S
D
L
D
F
K
I
K
R
E
K
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
25.8
93.2
92.5
N.A.
86.8
N.A.
N.A.
32.1
27
31.6
N.A.
N.A.
29.7
N.A.
N.A.
40.3
Protein Similarity:
100
41.2
94.1
95.9
N.A.
92.7
N.A.
N.A.
33.6
45.8
52.1
N.A.
N.A.
46.2
N.A.
N.A.
55
P-Site Identity:
100
20
0
100
N.A.
93.3
N.A.
N.A.
0
6.6
33.3
N.A.
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
26.6
26.6
100
N.A.
100
N.A.
N.A.
0
26.6
53.3
N.A.
N.A.
13.3
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
24
24.8
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
41.3
46.5
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
20
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
34
17
25
17
9
9
9
0
0
0
9
0
9
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% C
% Asp:
42
0
0
0
9
0
17
0
9
0
0
25
25
9
0
% D
% Glu:
0
9
9
17
0
0
0
9
0
0
9
9
17
9
9
% E
% Phe:
0
0
0
0
0
0
0
25
0
0
9
0
0
0
0
% F
% Gly:
9
9
0
0
0
9
17
0
9
9
0
0
25
9
0
% G
% His:
0
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
9
17
0
9
9
0
0
9
9
9
0
0
0
0
% I
% Lys:
0
0
0
17
0
0
0
0
9
9
9
17
9
9
0
% K
% Leu:
17
0
25
0
9
9
9
0
0
34
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
0
9
17
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
17
% N
% Pro:
9
0
0
0
0
9
0
0
0
0
9
0
0
0
25
% P
% Gln:
0
0
0
0
0
9
0
9
0
0
25
9
0
0
0
% Q
% Arg:
0
0
0
9
0
9
34
0
0
9
0
17
0
0
0
% R
% Ser:
9
9
0
17
0
0
0
9
0
9
0
0
0
34
9
% S
% Thr:
0
0
9
0
0
34
0
0
9
0
0
0
0
9
9
% T
% Val:
9
25
17
0
50
0
0
0
34
0
25
9
0
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
9
25
0
9
0
0
9
0
9
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _