KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ERAP2
All Species:
11.82
Human Site:
S522
Identified Species:
28.89
UniProt:
Q6P179
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P179
NP_001123612.1
960
110462
S522
H
S
D
P
K
M
T
S
N
M
L
A
F
L
G
Chimpanzee
Pan troglodytes
XP_001137768
960
110321
S522
H
S
D
P
K
M
T
S
N
M
L
A
F
L
G
Rhesus Macaque
Macaca mulatta
XP_001095247
946
108568
S508
H
S
D
P
K
M
T
S
N
M
L
T
F
L
G
Dog
Lupus familis
XP_546014
952
109111
N515
S
N
S
K
M
T
S
N
I
L
A
F
L
G
E
Cat
Felis silvestris
Mouse
Mus musculus
Q9EQH2
930
106581
S495
S
R
S
Q
H
S
S
S
T
S
H
W
R
Q
E
Rat
Rattus norvegicus
Q9JJ22
930
106401
S495
S
R
N
Q
H
S
S
S
T
S
H
W
R
Q
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512339
968
110122
T504
C
S
R
S
Q
R
K
T
S
T
S
H
W
T
Q
Chicken
Gallus gallus
XP_001232418
1131
127728
N692
S
D
G
F
C
R
R
N
Q
Q
S
S
S
N
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001116524
931
106878
K496
Y
S
S
A
Q
A
T
K
N
A
Y
R
F
A
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P32454
935
105566
M538
G
K
D
V
R
S
V
M
N
I
W
T
K
K
V
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.3
94
81.3
N.A.
49.2
48
N.A.
49.6
43.2
N.A.
56.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.7
96.2
89.6
N.A.
67.1
66.8
N.A.
67.5
59.2
N.A.
72.8
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
93.3
0
N.A.
6.6
6.6
N.A.
6.6
0
N.A.
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
93.3
26.6
N.A.
13.3
20
N.A.
33.3
13.3
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
30.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
48.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
10
0
0
0
10
10
20
0
10
10
% A
% Cys:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
40
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
30
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
10
40
0
0
% F
% Gly:
10
0
10
0
0
0
0
0
0
0
0
0
0
10
40
% G
% His:
30
0
0
0
20
0
0
0
0
0
20
10
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% I
% Lys:
0
10
0
10
30
0
10
10
0
0
0
0
10
10
0
% K
% Leu:
0
0
0
0
0
0
0
0
0
10
30
0
10
30
0
% L
% Met:
0
0
0
0
10
30
0
10
0
30
0
0
0
0
0
% M
% Asn:
0
10
10
0
0
0
0
20
50
0
0
0
0
10
0
% N
% Pro:
0
0
0
30
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
20
20
0
0
0
10
10
0
0
0
20
10
% Q
% Arg:
0
20
10
0
10
20
10
0
0
0
0
10
20
0
0
% R
% Ser:
40
50
30
10
0
30
30
50
10
20
20
10
10
0
0
% S
% Thr:
0
0
0
0
0
10
40
10
20
10
0
20
0
10
0
% T
% Val:
0
0
0
10
0
0
10
0
0
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
10
20
10
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _