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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERAP2 All Species: 13.03
Human Site: S692 Identified Species: 31.85
UniProt: Q6P179 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P179 NP_001123612.1 960 110462 S692 Y Y L Q H E T S S P A L L E G
Chimpanzee Pan troglodytes XP_001137768 960 110321 S692 Y Y L Q H E T S S P A L L E G
Rhesus Macaque Macaca mulatta XP_001095247 946 108568 S678 H Y L Q H E T S S P A L L K G
Dog Lupus familis XP_546014 952 109111 S684 R Y L Q H E T S I P A L L K G
Cat Felis silvestris
Mouse Mus musculus Q9EQH2 930 106581 E658 L Y L K N E T E I M P I F Q A
Rat Rattus norvegicus Q9JJ22 930 106401 E658 L Y L K N E T E I M P I F Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512339 968 110122 Q668 L Y L K H E S Q I M P V F Q G
Chicken Gallus gallus XP_001232418 1131 127728 Q862 S Y M K R E T Q I M P I L Q G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001116524 931 106878 H666 A Y L K S E T H N V P L L Q G
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32454 935 105566 I689 S F V V W D Q I I N S I S S M
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 94 81.3 N.A. 49.2 48 N.A. 49.6 43.2 N.A. 56.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 96.2 89.6 N.A. 67.1 66.8 N.A. 67.5 59.2 N.A. 72.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 86.6 80 N.A. 26.6 33.3 N.A. 33.3 33.3 N.A. 46.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 86.6 N.A. 53.3 60 N.A. 60 60 N.A. 66.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 0 0 40 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 90 0 20 0 0 0 0 0 20 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 30 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 80 % G
% His: 10 0 0 0 50 0 0 10 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 10 60 0 0 40 0 0 0 % I
% Lys: 0 0 0 50 0 0 0 0 0 0 0 0 0 20 0 % K
% Leu: 30 0 80 0 0 0 0 0 0 0 0 50 60 0 0 % L
% Met: 0 0 10 0 0 0 0 0 0 40 0 0 0 0 10 % M
% Asn: 0 0 0 0 20 0 0 0 10 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 40 50 0 0 0 0 % P
% Gln: 0 0 0 40 0 0 10 20 0 0 0 0 0 50 0 % Q
% Arg: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 20 0 0 0 10 0 10 40 30 0 10 0 10 10 0 % S
% Thr: 0 0 0 0 0 0 80 0 0 0 0 0 0 0 0 % T
% Val: 0 0 10 10 0 0 0 0 0 10 0 10 0 0 0 % V
% Trp: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 20 90 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _