Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ERAP2 All Species: 30.3
Human Site: S744 Identified Species: 74.07
UniProt: Q6P179 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q6P179 NP_001123612.1 960 110462 S744 Q S W S D K G S V W D R M L R
Chimpanzee Pan troglodytes XP_001137768 960 110321 S744 Q S W S D K G S V W D R M L R
Rhesus Macaque Macaca mulatta XP_001095247 946 108568 S730 Q S W S D E G S V W D R M L R
Dog Lupus familis XP_546014 952 109111 S736 Q S W S D K G S V W D R L L R
Cat Felis silvestris
Mouse Mus musculus Q9EQH2 930 106581 S710 Q T W T D E G S V S E R M L R
Rat Rattus norvegicus Q9JJ22 930 106401 S710 Q T W T D E G S V S E R M L R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512339 968 110122 S720 Q S W S D E G S V S E R M L R
Chicken Gallus gallus XP_001232418 1131 127728 S914 Q L W S D E G S V S E R M L R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001116524 931 106878 M718 Q S W S D D G M V S D R R L R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32454 935 105566 L741 D S F S T Q R L K V T M F G A
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.3 94 81.3 N.A. 49.2 48 N.A. 49.6 43.2 N.A. 56.6 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.7 96.2 89.6 N.A. 67.1 66.8 N.A. 67.5 59.2 N.A. 72.8 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 93.3 93.3 N.A. 66.6 66.6 N.A. 80 73.3 N.A. 73.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 93.3 93.3 N.A. 93.3 86.6 N.A. 73.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30.2 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 48.7 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 90 10 0 0 0 0 50 0 0 0 0 % D
% Glu: 0 0 0 0 0 50 0 0 0 0 40 0 0 0 0 % E
% Phe: 0 0 10 0 0 0 0 0 0 0 0 0 10 0 0 % F
% Gly: 0 0 0 0 0 0 90 0 0 0 0 0 0 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 30 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 10 0 0 0 0 0 10 0 0 0 0 10 90 0 % L
% Met: 0 0 0 0 0 0 0 10 0 0 0 10 70 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 90 0 0 0 0 10 0 0 0 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 10 0 0 0 0 90 10 0 90 % R
% Ser: 0 70 0 80 0 0 0 80 0 50 0 0 0 0 0 % S
% Thr: 0 20 0 20 10 0 0 0 0 0 10 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 90 10 0 0 0 0 0 % V
% Trp: 0 0 90 0 0 0 0 0 0 40 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _