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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDC73
All Species:
37.58
Human Site:
S500
Identified Species:
68.89
UniProt:
Q6P1J9
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P1J9
NP_078805.3
531
60577
S500
D
V
T
V
L
E
L
S
Y
H
K
R
H
L
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001112520
355
40602
Y325
V
T
V
L
E
L
S
Y
H
K
R
H
L
D
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
NP_666103
531
60558
S500
D
V
T
V
L
E
L
S
Y
H
K
R
H
L
D
Rat
Rattus norvegicus
Q4V8C8
531
60584
S500
D
V
T
V
L
E
L
S
Y
H
K
R
H
L
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516577
745
82627
S714
D
V
T
V
L
E
L
S
Y
H
K
R
H
L
D
Chicken
Gallus gallus
Q5ZLM0
531
60679
S500
D
V
T
V
L
E
L
S
Y
H
K
R
H
L
D
Frog
Xenopus laevis
NP_001079512
531
60663
S500
D
V
T
L
L
E
L
S
Y
H
K
R
H
L
D
Zebra Danio
Brachydanio rerio
NP_956642
521
59412
A474
D
I
F
A
K
I
R
A
F
H
L
K
Y
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649863
538
61366
S507
S
V
T
L
L
R
L
S
Q
N
K
R
H
M
D
Honey Bee
Apis mellifera
XP_395835
525
59540
S494
A
V
T
V
I
E
L
S
R
T
K
R
H
L
D
Nematode Worm
Caenorhab. elegans
NP_500465
535
60290
S500
N
V
H
K
I
P
V
S
A
T
K
R
H
M
D
Sea Urchin
Strong. purpuratus
XP_001192448
532
61126
S501
N
V
H
V
M
D
L
S
R
S
K
R
H
L
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q06697
393
44438
L364
W
N
V
E
K
V
E
L
D
K
N
K
R
F
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
66.8
N.A.
N.A.
100
99.8
N.A.
67.6
97.7
93.9
88.8
N.A.
58.5
65.1
30.8
62.5
Protein Similarity:
100
N.A.
66.8
N.A.
N.A.
100
99.8
N.A.
70
98.6
96.6
92.6
N.A.
73.4
77.5
52.7
75.3
P-Site Identity:
100
N.A.
0
N.A.
N.A.
100
100
N.A.
100
100
93.3
13.3
N.A.
60
73.3
40
60
P-Site Similarity:
100
N.A.
20
N.A.
N.A.
100
100
N.A.
100
100
100
53.3
N.A.
80
80
66.6
80
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
8
0
0
0
8
8
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
54
0
0
0
0
8
0
0
8
0
0
0
0
16
77
% D
% Glu:
0
0
0
8
8
54
8
0
0
0
0
0
0
0
8
% E
% Phe:
0
0
8
0
0
0
0
0
8
0
0
0
0
8
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
16
0
0
0
0
0
8
54
0
8
77
0
0
% H
% Ile:
0
8
0
0
16
8
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
8
16
0
0
0
0
16
77
16
0
0
8
% K
% Leu:
0
0
0
24
54
8
70
8
0
0
8
0
8
62
0
% L
% Met:
0
0
0
0
8
0
0
0
0
0
0
0
0
16
0
% M
% Asn:
16
8
0
0
0
0
0
0
0
8
8
0
0
0
0
% N
% Pro:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
8
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
8
8
0
16
0
8
77
8
0
8
% R
% Ser:
8
0
0
0
0
0
8
77
0
8
0
0
0
0
0
% S
% Thr:
0
8
62
0
0
0
0
0
0
16
0
0
0
0
0
% T
% Val:
8
77
16
54
0
8
8
0
0
0
0
0
0
0
0
% V
% Trp:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
47
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _