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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H2C
All Species:
38.79
Human Site:
S121
Identified Species:
65.64
UniProt:
Q6P1K8
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P1K8
NP_001035955.1
395
44452
S121
A
E
K
L
T
E
L
S
G
N
P
R
K
H
I
Chimpanzee
Pan troglodytes
XP_001157963
395
44404
S121
A
E
K
L
T
E
L
S
G
N
P
R
K
H
V
Rhesus Macaque
Macaca mulatta
XP_001095474
395
44419
S121
A
E
K
L
T
E
L
S
G
N
P
R
K
H
I
Dog
Lupus familis
XP_535266
395
44483
S121
A
E
K
L
T
E
L
S
G
N
P
R
K
H
I
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIB4
396
44669
S121
A
E
K
L
T
E
L
S
G
N
P
R
K
H
I
Rat
Rattus norvegicus
A0JN27
396
44685
S121
A
E
K
L
T
E
L
S
G
N
P
R
K
H
I
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512459
470
52108
S196
A
E
K
L
T
E
L
S
G
N
P
R
K
H
T
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085329
395
44828
A121
A
E
K
L
T
E
L
A
G
N
P
R
Q
H
I
Zebra Danio
Brachydanio rerio
NP_963875
392
44051
A121
A
E
K
L
T
D
L
A
G
N
P
K
K
H
I
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649427
438
48601
T124
A
E
K
V
T
E
L
T
G
T
S
R
V
H
L
Honey Bee
Apis mellifera
XP_394997
405
45681
T122
A
E
K
V
S
E
L
T
G
N
S
K
K
H
I
Nematode Worm
Caenorhab. elegans
P34567
376
41593
Q107
F
E
Q
N
P
I
A
Q
I
G
L
I
T
C
K
Sea Urchin
Strong. purpuratus
XP_782325
476
53839
G122
A
E
K
L
T
E
L
G
G
N
P
Q
R
H
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04673
461
52272
S186
A
Q
L
V
S
Q
V
S
G
N
P
Q
D
H
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.4
97.9
N.A.
96.7
96.2
N.A.
77.4
N.A.
83.5
80.7
N.A.
48.8
50.1
42.2
50.4
Protein Similarity:
100
100
100
98.9
N.A.
97.9
97.4
N.A.
80.8
N.A.
93.4
91.1
N.A.
65
69.1
62.5
63.4
P-Site Identity:
100
93.3
100
100
N.A.
100
100
N.A.
93.3
N.A.
86.6
80
N.A.
60
66.6
6.6
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
93.3
N.A.
100
100
N.A.
80
93.3
13.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
86.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
93
0
0
0
0
0
8
15
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% D
% Glu:
0
93
0
0
0
79
0
0
0
0
0
0
0
0
0
% E
% Phe:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
8
93
8
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
93
0
% H
% Ile:
0
0
0
0
0
8
0
0
8
0
0
8
0
0
72
% I
% Lys:
0
0
86
0
0
0
0
0
0
0
0
15
65
0
8
% K
% Leu:
0
0
8
72
0
0
86
0
0
0
8
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
0
0
86
0
0
0
0
0
% N
% Pro:
0
0
0
0
8
0
0
0
0
0
79
0
0
0
0
% P
% Gln:
0
8
8
0
0
8
0
8
0
0
0
15
8
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
65
8
0
0
% R
% Ser:
0
0
0
0
15
0
0
58
0
0
15
0
0
0
0
% S
% Thr:
0
0
0
0
79
0
0
15
0
8
0
0
8
0
8
% T
% Val:
0
0
0
22
0
0
8
0
0
0
0
0
8
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _