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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H2C
All Species:
26.06
Human Site:
S237
Identified Species:
44.1
UniProt:
Q6P1K8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P1K8
NP_001035955.1
395
44452
S237
E
L
L
T
H
H
L
S
P
P
P
A
S
S
S
Chimpanzee
Pan troglodytes
XP_001157963
395
44404
S237
E
L
L
T
H
H
V
S
P
P
P
A
S
S
S
Rhesus Macaque
Macaca mulatta
XP_001095474
395
44419
S237
E
L
L
T
H
H
V
S
P
P
P
A
S
S
S
Dog
Lupus familis
XP_535266
395
44483
S237
E
L
L
T
H
H
V
S
P
P
P
A
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIB4
396
44669
S237
E
L
L
A
H
H
V
S
P
P
P
A
S
S
S
Rat
Rattus norvegicus
A0JN27
396
44685
S237
E
L
L
A
R
H
V
S
P
P
P
A
S
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512459
470
52108
S312
E
L
L
I
H
H
V
S
P
P
P
A
S
S
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085329
395
44828
I237
E
L
L
M
H
H
V
I
P
P
P
A
S
S
S
Zebra Danio
Brachydanio rerio
NP_963875
392
44051
K237
E
L
L
L
L
H
V
K
P
P
P
A
S
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649427
438
48601
D240
D
Q
L
M
S
Q
V
D
P
P
P
A
A
K
T
Honey Bee
Apis mellifera
XP_394997
405
45681
D238
E
Q
L
N
M
H
I
D
P
P
P
A
A
T
R
Nematode Worm
Caenorhab. elegans
P34567
376
41593
Y223
A
K
A
T
K
G
E
Y
S
V
A
L
D
P
D
Sea Urchin
Strong. purpuratus
XP_782325
476
53839
I238
E
L
L
M
E
H
T
I
P
P
P
A
R
V
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04673
461
52272
N302
T
H
L
K
E
L
F
N
E
A
V
T
P
L
P
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.4
97.9
N.A.
96.7
96.2
N.A.
77.4
N.A.
83.5
80.7
N.A.
48.8
50.1
42.2
50.4
Protein Similarity:
100
100
100
98.9
N.A.
97.9
97.4
N.A.
80.8
N.A.
93.4
91.1
N.A.
65
69.1
62.5
63.4
P-Site Identity:
100
93.3
93.3
93.3
N.A.
86.6
73.3
N.A.
86.6
N.A.
80
73.3
N.A.
33.3
46.6
6.6
53.3
P-Site Similarity:
100
100
100
100
N.A.
93.3
80
N.A.
93.3
N.A.
86.6
80
N.A.
60
66.6
6.6
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
15
0
0
0
0
0
8
8
86
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
8
0
0
0
0
0
0
15
0
0
0
0
8
0
8
% D
% Glu:
79
0
0
0
15
0
8
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
8
% G
% His:
0
8
0
0
50
79
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
8
15
0
0
0
0
0
0
0
% I
% Lys:
0
8
0
8
8
0
0
8
0
0
0
0
0
8
0
% K
% Leu:
0
72
93
8
8
8
8
0
0
0
0
8
0
8
0
% L
% Met:
0
0
0
22
8
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
8
0
0
0
8
0
0
0
0
0
0
8
% N
% Pro:
0
0
0
0
0
0
0
0
86
86
86
0
8
8
8
% P
% Gln:
0
15
0
0
0
8
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
8
% R
% Ser:
0
0
0
0
8
0
0
50
8
0
0
0
65
65
58
% S
% Thr:
8
0
0
36
0
0
8
0
0
0
0
8
0
8
8
% T
% Val:
0
0
0
0
0
0
65
0
0
8
8
0
0
8
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _