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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H2C
All Species:
40.61
Human Site:
S29
Identified Species:
68.72
UniProt:
Q6P1K8
Number Species:
13
Phosphosite Substitution
Charge Score:
0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P1K8
NP_001035955.1
395
44452
S29
L
K
E
D
E
S
G
S
L
K
A
T
I
E
D
Chimpanzee
Pan troglodytes
XP_001157963
395
44404
S29
L
K
E
D
E
S
G
S
L
K
A
T
I
E
D
Rhesus Macaque
Macaca mulatta
XP_001095474
395
44419
S29
L
K
E
D
E
S
G
S
L
K
A
T
I
E
D
Dog
Lupus familis
XP_535266
395
44483
S29
L
K
E
D
E
S
G
S
L
K
A
T
I
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIB4
396
44669
S29
L
K
E
D
E
T
G
S
L
K
A
T
I
E
D
Rat
Rattus norvegicus
A0JN27
396
44685
S29
L
K
E
D
E
S
G
S
L
K
A
T
I
E
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512459
470
52108
S104
L
K
E
D
E
S
G
S
L
K
A
T
I
E
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085329
395
44828
S29
L
K
E
D
E
S
G
S
L
K
A
T
I
D
E
Zebra Danio
Brachydanio rerio
NP_963875
392
44051
S29
L
K
E
D
E
S
G
S
L
K
A
T
V
E
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649427
438
48601
M32
I
K
D
D
E
D
G
M
L
D
G
A
I
A
E
Honey Bee
Apis mellifera
XP_394997
405
45681
L30
I
K
E
D
D
H
G
L
L
E
A
S
V
A
D
Nematode Worm
Caenorhab. elegans
P34567
376
41593
E29
N
D
V
L
V
E
D
E
G
G
S
I
E
K
S
Sea Urchin
Strong. purpuratus
XP_782325
476
53839
S30
L
Q
E
D
E
E
G
S
L
Q
A
T
V
D
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04673
461
52272
D94
V
K
V
D
D
E
G
D
M
A
S
L
V
A
S
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.4
97.9
N.A.
96.7
96.2
N.A.
77.4
N.A.
83.5
80.7
N.A.
48.8
50.1
42.2
50.4
Protein Similarity:
100
100
100
98.9
N.A.
97.9
97.4
N.A.
80.8
N.A.
93.4
91.1
N.A.
65
69.1
62.5
63.4
P-Site Identity:
100
100
100
100
N.A.
93.3
100
N.A.
100
N.A.
86.6
93.3
N.A.
40
46.6
0
66.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
N.A.
100
100
N.A.
60
80
13.3
93.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
20
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
8
79
8
0
22
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
8
8
93
15
8
8
8
0
8
0
0
0
15
72
% D
% Glu:
0
0
79
0
79
22
0
8
0
8
0
0
8
58
15
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
93
0
8
8
8
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
0
0
0
0
0
0
0
0
0
0
8
65
0
0
% I
% Lys:
0
86
0
0
0
0
0
0
0
65
0
0
0
8
0
% K
% Leu:
72
0
0
8
0
0
0
8
86
0
0
8
0
0
0
% L
% Met:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% M
% Asn:
8
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
8
0
0
0
0
0
0
0
8
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
58
0
72
0
0
15
8
0
0
15
% S
% Thr:
0
0
0
0
0
8
0
0
0
0
0
72
0
0
0
% T
% Val:
8
0
15
0
8
0
0
0
0
0
0
0
29
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _