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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H2C
All Species:
35.45
Human Site:
Y298
Identified Species:
60
UniProt:
Q6P1K8
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.15
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P1K8
NP_001035955.1
395
44452
Y298
C
P
Q
C
R
A
K
Y
C
E
L
P
V
E
C
Chimpanzee
Pan troglodytes
XP_001157963
395
44404
Y298
C
P
Q
C
R
A
K
Y
C
E
L
P
V
E
C
Rhesus Macaque
Macaca mulatta
XP_001095474
395
44419
Y298
C
P
Q
C
R
A
K
Y
C
E
L
P
V
E
C
Dog
Lupus familis
XP_535266
395
44483
Y298
C
P
Q
C
R
A
K
Y
C
E
L
P
V
E
C
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIB4
396
44669
K298
F
C
P
Q
C
R
A
K
Y
C
E
L
P
V
E
Rat
Rattus norvegicus
A0JN27
396
44685
K298
F
C
P
Q
C
R
A
K
Y
C
E
L
P
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512459
470
52108
Y373
C
P
Q
C
R
A
K
Y
C
E
L
P
V
E
C
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085329
395
44828
Y298
C
P
Q
C
K
A
K
Y
S
E
L
P
V
E
C
Zebra Danio
Brachydanio rerio
NP_963875
392
44051
Y298
C
P
Q
C
R
A
K
Y
T
E
L
P
V
E
C
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649427
438
48601
Y301
C
P
Q
C
N
S
K
Y
C
E
L
P
V
E
C
Honey Bee
Apis mellifera
XP_394997
405
45681
H299
C
P
Q
C
L
S
K
H
C
E
L
P
V
E
C
Nematode Worm
Caenorhab. elegans
P34567
376
41593
F284
K
P
I
S
S
R
G
F
I
C
T
Q
C
G
A
Sea Urchin
Strong. purpuratus
XP_782325
476
53839
Y299
C
P
Q
C
Q
S
K
Y
C
E
L
P
V
E
C
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04673
461
52272
C363
V
C
S
L
P
T
V
C
P
C
C
D
L
M
L
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.4
97.9
N.A.
96.7
96.2
N.A.
77.4
N.A.
83.5
80.7
N.A.
48.8
50.1
42.2
50.4
Protein Similarity:
100
100
100
98.9
N.A.
97.9
97.4
N.A.
80.8
N.A.
93.4
91.1
N.A.
65
69.1
62.5
63.4
P-Site Identity:
100
100
100
100
N.A.
0
0
N.A.
100
N.A.
86.6
93.3
N.A.
86.6
80
6.6
86.6
P-Site Similarity:
100
100
100
100
N.A.
0
0
N.A.
100
N.A.
93.3
93.3
N.A.
93.3
93.3
13.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
50
15
0
0
0
0
0
0
0
8
% A
% Cys:
72
22
0
72
15
0
0
8
58
29
8
0
8
0
72
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
8
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
72
15
0
0
72
15
% E
% Phe:
15
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
8
0
0
0
0
0
0
8
0
% G
% His:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
8
0
0
0
8
0
72
15
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
8
8
0
0
0
0
0
72
15
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% M
% Asn:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
79
15
0
8
0
0
0
8
0
0
72
15
0
0
% P
% Gln:
0
0
72
15
8
0
0
0
0
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
43
22
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
8
8
8
22
0
0
8
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
0
8
0
0
8
0
8
0
0
0
0
% T
% Val:
8
0
0
0
0
0
8
0
0
0
0
0
72
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
65
15
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _