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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2H2C
All Species:
34.55
Human Site:
Y358
Identified Species:
58.46
UniProt:
Q6P1K8
Number Species:
13
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P1K8
NP_001035955.1
395
44452
Y358
E
L
K
D
Q
H
V
Y
V
C
A
V
C
Q
N
Chimpanzee
Pan troglodytes
XP_001157963
395
44404
Y358
E
L
K
D
Q
H
V
Y
V
C
A
V
C
Q
N
Rhesus Macaque
Macaca mulatta
XP_001095474
395
44419
Y358
E
L
K
D
Q
H
V
Y
V
C
A
V
C
Q
N
Dog
Lupus familis
XP_535266
395
44483
Y358
E
L
K
D
Q
H
V
Y
V
C
A
V
C
Q
N
Cat
Felis silvestris
Mouse
Mus musculus
Q9JIB4
396
44669
Y359
E
L
K
D
Q
H
V
Y
V
C
T
V
C
Q
N
Rat
Rattus norvegicus
A0JN27
396
44685
Y359
E
L
K
D
Q
H
V
Y
V
C
T
V
C
R
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512459
470
52108
Y433
E
L
K
D
Q
Q
V
Y
I
C
T
V
C
Q
S
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001085329
395
44828
Y358
E
L
K
D
Q
Q
V
Y
V
C
T
V
C
Q
C
Zebra Danio
Brachydanio rerio
NP_963875
392
44051
F358
E
L
K
D
K
S
V
F
T
C
L
A
C
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649427
438
48601
F376
K
V
A
D
K
V
V
F
R
C
G
F
C
K
Q
Honey Bee
Apis mellifera
XP_394997
405
45681
Y364
S
Q
K
D
K
K
V
Y
I
C
N
K
C
N
Q
Nematode Worm
Caenorhab. elegans
P34567
376
41593
G345
A
C
E
T
R
L
S
G
E
G
F
R
C
G
S
Sea Urchin
Strong. purpuratus
XP_782325
476
53839
Y428
H
I
R
D
Q
T
A
Y
R
C
P
K
C
S
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q04673
461
52272
L422
N
H
K
N
G
K
L
L
T
S
S
R
Y
R
C
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
99.4
97.9
N.A.
96.7
96.2
N.A.
77.4
N.A.
83.5
80.7
N.A.
48.8
50.1
42.2
50.4
Protein Similarity:
100
100
100
98.9
N.A.
97.9
97.4
N.A.
80.8
N.A.
93.4
91.1
N.A.
65
69.1
62.5
63.4
P-Site Identity:
100
100
100
100
N.A.
93.3
86.6
N.A.
73.3
N.A.
80
46.6
N.A.
26.6
40
6.6
40
P-Site Similarity:
100
100
100
100
N.A.
93.3
93.3
N.A.
86.6
N.A.
80
66.6
N.A.
60
53.3
26.6
53.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
36.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
52
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
8
0
0
0
8
0
0
0
29
8
0
0
0
% A
% Cys:
0
8
0
0
0
0
0
0
0
86
0
0
93
0
15
% C
% Asp:
0
0
0
86
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
65
0
8
0
0
0
0
0
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
15
0
0
8
8
0
0
0
% F
% Gly:
0
0
0
0
8
0
0
8
0
8
8
0
0
8
0
% G
% His:
8
8
0
0
0
43
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
8
0
0
0
0
0
0
15
0
0
0
0
0
0
% I
% Lys:
8
0
79
0
22
15
0
0
0
0
0
15
0
15
8
% K
% Leu:
0
65
0
0
0
8
8
8
0
0
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
8
0
0
8
0
0
0
0
0
0
8
0
0
8
50
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
8
0
0
0
0
% P
% Gln:
0
8
0
0
65
15
0
0
0
0
0
0
0
50
15
% Q
% Arg:
0
0
8
0
8
0
0
0
15
0
0
15
0
15
0
% R
% Ser:
8
0
0
0
0
8
8
0
0
8
8
0
0
8
15
% S
% Thr:
0
0
0
8
0
8
0
0
15
0
29
0
0
0
0
% T
% Val:
0
8
0
0
0
8
79
0
50
0
0
58
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
72
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _