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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CC2D1A
All Species:
8.48
Human Site:
S220
Identified Species:
16.97
UniProt:
Q6P1N0
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P1N0
NP_060191.3
951
104062
S220
Q
P
A
P
R
I
A
S
A
P
E
P
R
V
T
Chimpanzee
Pan troglodytes
XP_524131
950
103811
S220
Q
P
A
P
G
I
A
S
A
P
E
P
R
V
T
Rhesus Macaque
Macaca mulatta
XP_001111234
889
96793
S220
Q
P
A
P
G
I
A
S
A
P
E
P
R
V
T
Dog
Lupus familis
XP_542027
950
104086
P220
Q
P
A
S
A
N
P
P
V
P
E
P
R
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1A6
943
103679
L213
H
T
Q
A
T
S
Q
L
A
S
V
S
P
P
A
Rat
Rattus norvegicus
Q66HA5
941
103568
L212
H
T
H
T
T
S
H
L
A
P
V
S
P
P
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001235393
875
97121
E235
Q
A
T
G
A
E
Q
E
N
S
E
D
S
V
G
Frog
Xenopus laevis
Q6PF54
864
95663
A216
Q
G
R
T
V
I
E
A
D
I
P
P
P
V
A
Zebra Danio
Brachydanio rerio
XP_692169
859
94055
D229
P
A
P
A
V
S
P
D
E
Q
E
E
C
D
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VKJ9
816
89019
I144
T
T
V
D
T
L
S
I
I
K
Q
R
L
E
M
Honey Bee
Apis mellifera
XP_396955
792
89420
L147
K
A
K
Q
E
N
E
L
S
R
A
R
R
F
N
Nematode Worm
Caenorhab. elegans
Q9U2M8
792
85482
K148
Q
L
H
V
Y
Y
M
K
A
H
K
S
A
E
Q
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.4
90.1
90.8
N.A.
82.4
82.6
N.A.
N.A.
41.9
42.3
43
N.A.
29.8
24
21.1
N.A.
Protein Similarity:
100
98.8
90.7
93.6
N.A.
87.5
87.9
N.A.
N.A.
57.7
57
59
N.A.
47.7
41.8
36.1
N.A.
P-Site Identity:
100
93.3
93.3
60
N.A.
6.6
13.3
N.A.
N.A.
20
26.6
6.6
N.A.
0
6.6
13.3
N.A.
P-Site Similarity:
100
93.3
93.3
60
N.A.
6.6
13.3
N.A.
N.A.
20
33.3
13.3
N.A.
20
20
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
25
34
17
17
0
25
9
50
0
9
0
9
0
25
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
9
0
0
% C
% Asp:
0
0
0
9
0
0
0
9
9
0
0
9
0
9
0
% D
% Glu:
0
0
0
0
9
9
17
9
9
0
50
9
0
17
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
9
0
% F
% Gly:
0
9
0
9
17
0
0
0
0
0
0
0
0
0
9
% G
% His:
17
0
17
0
0
0
9
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
34
0
9
9
9
0
0
0
0
0
% I
% Lys:
9
0
9
0
0
0
0
9
0
9
9
0
0
0
0
% K
% Leu:
0
9
0
0
0
9
0
25
0
0
0
0
9
0
0
% L
% Met:
0
0
0
0
0
0
9
0
0
0
0
0
0
0
9
% M
% Asn:
0
0
0
0
0
17
0
0
9
0
0
0
0
0
9
% N
% Pro:
9
34
9
25
0
0
17
9
0
42
9
42
25
17
0
% P
% Gln:
59
0
9
9
0
0
17
0
0
9
9
0
0
0
9
% Q
% Arg:
0
0
9
0
9
0
0
0
0
9
0
17
42
0
0
% R
% Ser:
0
0
0
9
0
25
9
25
9
17
0
25
9
0
9
% S
% Thr:
9
25
9
17
25
0
0
0
0
0
0
0
0
0
34
% T
% Val:
0
0
9
9
17
0
0
0
9
0
17
0
0
50
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _