KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL2B
All Species:
14.85
Human Site:
S147
Identified Species:
27.22
UniProt:
Q6P1Q9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P1Q9
NP_060866.2
378
43440
S147
Q
H
K
C
S
S
K
S
L
E
H
K
T
Q
T
Chimpanzee
Pan troglodytes
XP_001152439
378
43448
S147
Q
H
K
C
S
L
K
S
L
E
H
K
T
Q
T
Rhesus Macaque
Macaca mulatta
XP_001116039
379
43675
S148
Q
H
K
C
S
S
K
S
L
E
H
K
T
E
T
Dog
Lupus familis
XP_537604
474
53846
S243
Q
H
K
C
S
S
N
S
L
G
H
K
M
Q
M
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMK1
389
43893
S140
Q
H
K
C
S
C
A
S
P
G
C
E
T
Q
V
Rat
Rattus norvegicus
Q6AXU8
287
33363
R65
K
D
R
H
W
T
T
R
E
F
E
E
L
R
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518238
377
41950
G146
G
S
C
G
D
A
F
G
L
P
V
S
D
S
R
Chicken
Gallus gallus
Q5ZHP8
370
42711
N140
T
L
E
N
R
A
E
N
Q
L
N
L
L
K
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8KBL7
353
40469
K131
H
L
R
G
A
E
E
K
E
S
L
E
H
M
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q86BS6
325
38113
H103
W
D
S
F
Y
G
I
H
D
N
R
F
F
K
D
Honey Bee
Apis mellifera
XP_624474
332
39379
Q110
L
A
V
D
I
V
K
Q
N
I
K
Q
P
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175658
397
45417
Q172
E
L
S
S
D
N
A
Q
A
S
A
K
E
C
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08641
628
71467
F402
P
A
R
Y
W
D
I
F
Y
K
N
N
K
E
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97
71.5
N.A.
78.1
34.3
N.A.
67.1
65
N.A.
65.6
N.A.
37.2
51
N.A.
43.5
Protein Similarity:
100
99.2
98.4
75.3
N.A.
84.8
46.5
N.A.
76.4
78.3
N.A.
76.9
N.A.
52.1
63.7
N.A.
59.9
P-Site Identity:
100
93.3
93.3
73.3
N.A.
53.3
0
N.A.
6.6
0
N.A.
0
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
93.3
100
73.3
N.A.
60
40
N.A.
13.3
46.6
N.A.
26.6
N.A.
6.6
13.3
N.A.
26.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
8
16
16
0
8
0
8
0
0
0
0
% A
% Cys:
0
0
8
39
0
8
0
0
0
0
8
0
0
8
0
% C
% Asp:
0
16
0
8
16
8
0
0
8
0
0
0
8
0
8
% D
% Glu:
8
0
8
0
0
8
16
0
16
24
8
24
8
16
0
% E
% Phe:
0
0
0
8
0
0
8
8
0
8
0
8
8
0
0
% F
% Gly:
8
0
0
16
0
8
0
8
0
16
0
0
0
0
0
% G
% His:
8
39
0
8
0
0
0
8
0
0
31
0
8
0
0
% H
% Ile:
0
0
0
0
8
0
16
0
0
8
0
0
0
0
0
% I
% Lys:
8
0
39
0
0
0
31
8
0
8
8
39
8
16
0
% K
% Leu:
8
24
0
0
0
8
0
0
39
8
8
8
16
8
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
8
8
% M
% Asn:
0
0
0
8
0
8
8
8
8
8
16
8
0
0
8
% N
% Pro:
8
0
0
0
0
0
0
0
8
8
0
0
8
0
0
% P
% Gln:
39
0
0
0
0
0
0
16
8
0
0
8
0
31
0
% Q
% Arg:
0
0
24
0
8
0
0
8
0
0
8
0
0
8
16
% R
% Ser:
0
8
16
8
39
24
0
39
0
16
0
8
0
8
24
% S
% Thr:
8
0
0
0
0
8
8
0
0
0
0
0
31
0
24
% T
% Val:
0
0
8
0
0
8
0
0
0
0
8
0
0
0
8
% V
% Trp:
8
0
0
0
16
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
8
0
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _