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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
METTL2B
All Species:
11.82
Human Site:
S22
Identified Species:
21.67
UniProt:
Q6P1Q9
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P1Q9
NP_060866.2
378
43440
S22
D
K
R
Q
Q
F
G
S
R
F
L
S
D
P
A
Chimpanzee
Pan troglodytes
XP_001152439
378
43448
S22
D
K
R
Q
Q
F
G
S
R
F
L
S
D
P
A
Rhesus Macaque
Macaca mulatta
XP_001116039
379
43675
N22
D
K
R
Q
Q
F
G
N
R
F
L
S
D
P
A
Dog
Lupus familis
XP_537604
474
53846
S117
E
K
R
Q
Q
F
G
S
R
F
L
S
D
P
A
Cat
Felis silvestris
Mouse
Mus musculus
Q8BMK1
389
43893
H22
G
K
R
P
Q
F
G
H
R
F
L
S
D
P
A
Rat
Rattus norvegicus
Q6AXU8
287
33363
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518238
377
41950
K26
A
A
A
A
E
E
G
K
R
P
P
F
G
T
R
Chicken
Gallus gallus
Q5ZHP8
370
42711
T20
P
F
G
R
R
F
L
T
D
P
T
R
L
F
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A8KBL7
353
40469
P17
S
P
V
I
E
N
M
P
E
T
A
G
G
A
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q86BS6
325
38113
Honey Bee
Apis mellifera
XP_624474
332
39379
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001175658
397
45417
T27
R
H
R
K
G
F
S
T
S
V
H
A
Y
Q
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q08641
628
71467
A167
D
E
S
E
E
E
S
A
N
N
A
S
E
P
A
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
97
71.5
N.A.
78.1
34.3
N.A.
67.1
65
N.A.
65.6
N.A.
37.2
51
N.A.
43.5
Protein Similarity:
100
99.2
98.4
75.3
N.A.
84.8
46.5
N.A.
76.4
78.3
N.A.
76.9
N.A.
52.1
63.7
N.A.
59.9
P-Site Identity:
100
100
93.3
93.3
N.A.
80
0
N.A.
13.3
6.6
N.A.
0
N.A.
0
0
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
80
0
N.A.
20
26.6
N.A.
6.6
N.A.
0
0
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
24.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
37.2
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
26.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
8
8
0
0
0
8
0
0
16
8
0
8
47
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
31
0
0
0
0
0
0
0
8
0
0
0
39
0
0
% D
% Glu:
8
8
0
8
24
16
0
0
8
0
0
0
8
0
0
% E
% Phe:
0
8
0
0
0
54
0
0
0
39
0
8
0
8
0
% F
% Gly:
8
0
8
0
8
0
47
0
0
0
0
8
16
0
0
% G
% His:
0
8
0
0
0
0
0
8
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
39
0
8
0
0
0
8
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
0
0
8
0
0
0
39
0
8
0
0
% L
% Met:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
8
0
8
8
8
0
0
0
0
0
% N
% Pro:
8
8
0
8
0
0
0
8
0
16
8
0
0
47
0
% P
% Gln:
0
0
0
31
39
0
0
0
0
0
0
0
0
8
8
% Q
% Arg:
8
0
47
8
8
0
0
0
47
0
0
8
0
0
8
% R
% Ser:
8
0
8
0
0
0
16
24
8
0
0
47
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
16
0
8
8
0
0
8
8
% T
% Val:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _