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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED27
All Species:
31.52
Human Site:
S136
Identified Species:
63.03
UniProt:
Q6P2C8
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q6P2C8
NP_004260.2
311
35432
S136
N
Q
Q
S
L
K
R
S
A
N
Q
M
G
V
S
Chimpanzee
Pan troglodytes
XP_526874
311
35434
S136
N
Q
Q
S
L
K
R
S
A
N
Q
M
G
V
S
Rhesus Macaque
Macaca mulatta
XP_001105126
311
35440
S136
N
Q
Q
S
L
K
R
S
A
N
Q
M
G
V
S
Dog
Lupus familis
XP_849826
311
35341
S136
N
Q
Q
S
L
K
R
S
A
N
Q
M
G
V
S
Cat
Felis silvestris
Mouse
Mus musculus
Q9DB40
311
35279
S136
N
Q
Q
S
L
K
R
S
A
N
Q
M
G
V
S
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506492
243
27824
A76
A
N
Q
M
G
V
S
A
K
R
R
P
K
A
Q
Chicken
Gallus gallus
XP_415455
312
35236
S137
N
Q
Q
S
L
K
R
S
A
N
Q
M
G
V
S
Frog
Xenopus laevis
Q3B8G8
311
35405
S136
N
Q
Q
S
L
K
R
S
A
I
Q
M
G
V
S
Zebra Danio
Brachydanio rerio
Q6PFL0
311
35653
S136
N
Q
Q
S
L
K
R
S
A
N
Q
M
G
T
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VNG0
293
33850
Y126
Q
N
T
L
R
R
S
Y
N
Y
C
S
Q
K
R
Honey Bee
Apis mellifera
XP_396939
298
33938
R131
L
S
Q
N
S
L
K
R
S
Y
N
T
T
S
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_780142
244
27952
G77
K
R
S
S
G
S
G
G
S
P
A
K
R
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
96.4
99.6
98
N.A.
98
N.A.
N.A.
77.4
94.2
89.3
88.4
N.A.
38.9
39.5
N.A.
36.3
Protein Similarity:
100
97.1
100
99.6
N.A.
99.6
N.A.
N.A.
77.8
97.7
93.8
93.5
N.A.
60.7
61.7
N.A.
54
P-Site Identity:
100
100
100
100
N.A.
100
N.A.
N.A.
6.6
100
93.3
93.3
N.A.
0
6.6
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
20
100
93.3
93.3
N.A.
6.6
26.6
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
9
67
0
9
0
0
9
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
17
0
9
9
0
0
0
0
67
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% I
% Lys:
9
0
0
0
0
67
9
0
9
0
0
9
9
9
9
% K
% Leu:
9
0
0
9
67
9
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
9
0
0
0
0
0
0
0
67
0
0
0
% M
% Asn:
67
17
0
9
0
0
0
0
9
59
9
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
9
0
9
0
0
0
% P
% Gln:
9
67
84
0
0
0
0
0
0
0
67
0
9
0
9
% Q
% Arg:
0
9
0
0
9
9
67
9
0
9
9
0
9
9
17
% R
% Ser:
0
9
9
75
9
9
17
67
17
0
0
9
0
9
67
% S
% Thr:
0
0
9
0
0
0
0
0
0
0
0
9
9
9
0
% T
% Val:
0
0
0
0
0
9
0
0
0
0
0
0
0
59
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
9
0
17
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _